1. Gene
  2. Gpd2 - glycerol phosphate dehydrogenase 2, mitochondrial Gene

Gpd2 - glycerol phosphate dehydrogenase 2, mitochondrial Gene

种属: Mus musculus

同用名: GPDH; Gdm1; Gpd-m; Gpdh-m; TISP38

基因 ID: 14571 | 基因类型: protein coding

关于 Gpd2

功能概要

Predicted to enable glycerol-3-phosphate dehydrogenase [NAD+] activity. Acts upstream of or within camera-type eye development; gluconeogenesis; and glycerol-3-phosphate metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Gpd2 基因产物(2)

mRNA Protein Name
NM_001145820.1 NP_001139292.1 glycerol-3-phosphate dehydrogenase, mitochondrial precursor
NM_010274.3 NP_034404.3 glycerol-3-phosphate dehydrogenase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycerol-3-phosphate dehydrogenase (quinone) activity IMP
IMP: 通过突变表型推断
9974390 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within camera-type eye development IGI
IGI: 通过遗传相互作用推断
21296886 MGI
acts upstream of or within gluconeogenesis IMP
IMP: 通过突变表型推断
12093800 MGI
acts upstream of or within glycerol-3-phosphate metabolic process IMP
IMP: 通过突变表型推断
12093800 MGI
involved in glycerophosphate shuttle IMP
IMP: 通过突变表型推断
9974390 MGI
acts upstream of or within multicellular organism growth IGI
IGI: 通过遗传相互作用推断
21296886 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial inner membrane IMP
IMP: 通过突变表型推断
12093799 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glycerol-3-phosphate dehydrogenase, mitochondrial

FAD-linked glycerol-3-phosphate dehydrogenase

glycerol phosphate dehydrogenase 1, mitochondrial

glycerol-3-phosphate dehydrogenase 2, mitochondrial

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpd2 NCBI NCBI:2820