1. Gene
  2. NCAN - neurocan Gene

NCAN - neurocan Gene

中文名称:神经元

种属: Homo sapiens

同用名: CSPG3

基因 ID: 1463 | 基因类型: protein coding

关于 NCAN

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:19,211,958-19,252,233 (from NCBI)

This gene has 4 transcripts (splice variants), 278 orthologues and 7 paralogues. Restricted expression toward brain (RPKM 74.5).

功能概要

Neurocan 是一种硫酸软骨素蛋白聚糖,被认为参与细胞粘附和迁移的调节。[OMIM 提供,2002 年 7 月]

Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002]

NCAN 基因产物(1)

mRNA Protein Name
NM_004386.3 NP_004377.2 neurocan core protein precursor

NCAN 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (45 - 145)

Xlink

Xlink: Extracellular link domain (159 - 254)

Xlink

Xlink: Extracellular link domain (260 - 356)

Lectin_C

Lectin_C: Lectin C-type domain (1107 - 1210)

Sushi

Sushi: Sushi repeat (SCR repeat) (1215 - 1271)

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  • 1321 a.a.
蛋白主名 其他名称

neurocan core protein

chondroitin sulfate proteoglycan 3 (neurocan)

NCAN 抗体

目录号 产品名 应用 反应物种
HY-P83101 Neurocan Antibody (YA2846) WB, IHC-P, IP Human

关联疾病

疾病名称 别名
Bipolar Disorder

Bipolar Depression

Manic Disorder

Depression, Bipolar

Bipolar Disorder Manic Phase

Depressive-Manic Psych.

Manic Bipolar Affective Disorder

Manic Bipolar I Disorder

Manic Depression

Manic Depressive Disorder

Mixed Bipolar Disorder

Bipolar Affective Disorder

Bipolar Affective Psychosis

Bipolar Spectrum Disorder

Manic Depressive Illness

Depression Bipolar

Bipolar Disorder, Mixed

Major Affective Disorder

Major Affective Disorder 1

Major Affective Disorder 2

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris NCAN VGNC VGNC:43638
Rattus norvegicus NCAN RGD RGD:619941
Felis catus NCAN VGNC VGNC:82375
Bos taurus NCAN VGNC VGNC:31900
Mus musculus NCAN MGD MGI:104694
Others NCAN NCBI