2. Gene
  3. Adgrg1 - adhesion G protein-coupled receptor G1 Gene

Adgrg1 - adhesion G protein-coupled receptor G1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cyt28; Gpr56; TM7LN4; TM7XN1

基因 ID: 14766 | 基因类型: protein coding

关于 Adgrg1

功能概要

Enables several functions, including Collagen binding activity; extracellular matrix binding activity; and heparin binding activity. Involved in several processes, including negative regulation of neuron migration; positive regulation of Rho protein signal transduction; and seminiferous tubule development. Acts upstream of or within cerebral cortex regionalization; hematopoietic stem cell homeostasis; and positive regulation of neural precursor cell proliferation. Located in glial limiting end-foot. Is expressed in several structures, including alimentary system; ganglia; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in bilateral frontoparietal polymicrogyria and bilateral perisylvian polymicrogyria. Orthologous to human ADGRG1 (adhesion G protein-coupled receptor G1). [provided by Alliance of Genome Resources, Apr 2022]

Adgrg1 基因产物(25)

mRNA Protein Name
NM_001198894.2 NP_001185823.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403764.1 NP_001390693.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403765.1 NP_001390694.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403766.1 NP_001390695.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403767.1 NP_001390696.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403768.1 NP_001390697.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403769.1 NP_001390698.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403770.1 NP_001390699.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403771.1 NP_001390700.1 adhesion G-protein coupled receptor G1 isoform a precursor
NM_001403772.1 NP_001390701.1 adhesion G-protein coupled receptor G1 isoform b precursor
NM_001403776.1 NP_001390705.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403778.1 NP_001390707.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403779.1 NP_001390708.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403780.1 NP_001390709.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403781.1 NP_001390710.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403782.1 NP_001390711.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403783.1 NP_001390712.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403784.1 NP_001390713.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403785.1 NP_001390714.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403786.1 NP_001390715.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403787.1 NP_001390716.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403788.1 NP_001390717.1 adhesion G-protein coupled receptor G1 isoform c precursor
NM_001403789.1 NP_001390718.1 adhesion G-protein coupled receptor G1 isoform d precursor
NM_001403790.1 NP_001390719.1 adhesion G-protein coupled receptor G1 isoform d precursor
NM_018882.4 NP_061370.2 adhesion G-protein coupled receptor G1 isoform c precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IMP
IMP: 通过突变表型推断
21768377 MGI
enables collagen binding IDA
IDA: 通过直接分析推断
21768377 MGI
enables extracellular matrix binding IDA
IDA: 通过直接分析推断
18509043 MGI
enables heparin binding IDA
IDA: 通过直接分析推断
27068534 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
36453010 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebral cortex radial glia-guided migration IMP
IMP: 通过突变表型推断
18509043 MGI
acts upstream of or within cerebral cortex regionalization IMP
IMP: 通过突变表型推断
24531968 MGI
acts upstream of or within hematopoietic stem cell homeostasis IMP
IMP: 通过突变表型推断
26880577 MGI
involved in layer formation in cerebral cortex IMP
IMP: 通过突变表型推断
18509043 MGI
involved in negative regulation of neuron migration IMP
IMP: 通过突变表型推断
18509043 MGI
acts upstream of neural precursor cell proliferation IMP
IMP: 通过突变表型推断
24531968 MGI
involved in positive regulation of Rho protein signal transduction IMP
IMP: 通过突变表型推断
21768377 MGI
acts upstream of or within positive regulation of neural precursor cell proliferation IMP
IMP: 通过突变表型推断
24531968 MGI
involved in seminiferous tubule development IMP
IMP: 通过突变表型推断
20981830 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in glial limiting end-foot IDA
IDA: 通过直接分析推断
18509043 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

adhesion G-protein coupled receptor G1

G-protein coupled receptor 56

secretin receptor

serpentine receptor cyt28

Adgrg1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Adgrg1 Q8K209 Adgrl1 Mus musculus Q80TR1
Anti Bait CoIP
36453010
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00354 ADGRG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20135 Adgrg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26638 Adgrg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adgrg1 NCBI NCBI:9289
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