1. Gene
  2. Guca1a - guanylate cyclase activator 1a (retina) Gene

Guca1a - guanylate cyclase activator 1a (retina) Gene

种属: Mus musculus

同用名: GC-A; Gcap1; Guca1; mGCAP1

基因 ID: 14913 | 基因类型: protein coding

关于 Guca1a

功能概要

This gene encodes a calcium-binding photoreceptor protein. The encoded protein may be involved in modulation of guanylyl cyclase activity, and in turn, the mammalian cone phototransduction cascade. Disruption of this gene results in the retinal degeneration associated with cone dystrophy. [provided by RefSeq, Dec 2015]

Guca1a 基因产物(1)

mRNA Protein Name
NM_008189.3 NP_032215.2 guanylyl cyclase-activating protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium sensitive guanylate cyclase activator activity IDA
IDA: 通过直接分析推断
11493703 MGI
enables guanylate cyclase regulator activity IGI
IGI: 通过遗传相互作用推断
15336959 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within phototransduction IMP
IMP: 通过突变表型推断
11493703 MGI
acts upstream of or within regulation of guanylate cyclase activity IGI
IGI: 通过遗传相互作用推断
15336959 MGI
acts upstream of or within visual perception IMP
IMP: 通过突变表型推断
11493703 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cone photoreceptor outer segment IDA
IDA: 通过直接分析推断
9620085 MGI
located in photoreceptor inner segment IDA
IDA: 通过直接分析推断
9620085 MGI
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
22183407 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

guanylyl cyclase-activating protein 1

GCAP 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Guca1a NCBI NCBI:2978