1. Gene
  2. Lef1 - lymphoid enhancer binding factor 1 Gene

Lef1 - lymphoid enhancer binding factor 1 Gene

种属: Rattus norvegicus

基因 ID: 161452 | 基因类型: protein coding

关于 Lef1

功能概要

Predicted to enable several functions, including DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and protein domain specific binding activity. Involved in several processes, including animal organ development; odontoblast differentiation; and response to lithium ion. Located in nucleus. Human ortholog(s) of this gene implicated in ovarian Cancer. Orthologous to human LEF1 (lymphoid enhancer binding factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lef1 基因产物(1)

mRNA Protein Name
NM_130429.2 NP_569113.2 lymphoid enhancer-binding factor 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17170212 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
18990226 RGD
involved in cell adhesion IEP
IEP: 通过表达模式推断
9539744 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
17329570 RGD
involved in odontoblast differentiation IMP
IMP: 通过突变表型推断
20425127 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17329570 RGD
involved in skin development IEP
IEP: 通过表达模式推断
17244330 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lymphoid enhancer-binding factor 1

LEF-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lef1 NCBI NCBI:51176