ECI1 - enoyl-CoA delta isomerase 1 Gene

中文名称：烯酰辅酶 A δ 异构酶 1

种属: Homo sapiens

同用名: DCI

关于 ECI1

功能概要

该基因编码水合酶/异构酶超家族的一个成员。所编码的蛋白质是参与不饱和脂肪酸 β 氧化的关键线粒体酶。它催化在顺式、单和多不饱和脂肪酸逐步降解为 2-反式烯酰辅酶 A 中间体过程中产生的 3-顺式和 3-反式烯酰辅酶 A 酯的转化。已经描述了选择性剪接的转录物变体。[RefSeq 提供，2010 年 5 月]

This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]