2. Gene
  3. Jag2 - jagged 2 Gene

Jag2 - jagged 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: sm; Serh; D12Ggc2e; mJagged2-1

基因 ID: 16450 | 基因类型: protein coding

关于 Jag2

功能概要

Enables Notch binding activity. Involved in auditory receptor cell fate commitment; gamma-delta T cell differentiation; and positive regulation of Notch signaling pathway. Acts upstream of or within several processes, including epithelial cell apoptotic process involved in palatal shelf morphogenesis; odontogenesis of dentin-containing tooth; and respiratory system process. Located in membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and surface ectoderm. Orthologous to human JAG2 (jagged canonical Notch ligand 2). [provided by Alliance of Genome Resources, Apr 2022]

Jag2 基因产物(2)

mRNA Protein Name
NM_001409685.1 NP_001396614.1 protein jagged-2 isoform 2 precursor
NM_010588.3 NP_034718.2 protein jagged-2 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Notch binding IPI
IPI: 通过物理相互作用推断
10958687 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12496659 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in auditory receptor cell fate commitment IMP
IMP: 通过突变表型推断
10080181 MGI
acts upstream of or within epithelial cell apoptotic process involved in palatal shelf morphogenesis IMP
IMP: 通过突变表型推断
16607638 MGI
involved in gamma-delta T cell differentiation IMP
IMP: 通过突变表型推断
10383933 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
9531541 MGI
acts upstream of or within morphogenesis of embryonic epithelium IMP
IMP: 通过突变表型推断
16607638 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: 通过突变表型推断
15721140 MGI
involved in positive regulation of Notch signaling pathway IDA
IDA: 通过直接分析推断
10958687 MGI
acts upstream of or within regulation of cell adhesion IMP
IMP: 通过突变表型推断
16607638 MGI
acts upstream of or within respiratory system process IMP
IMP: 通过突变表型推断
9531541 MGI
acts upstream of or within skeletal system development IMP
IMP: 通过突变表型推断
15721140 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
15886206 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10910909 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein jagged-2

syndactylism

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07013 JAG2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19343 Jag2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25834 Jag2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jag2 NCBI NCBI:3714
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