2. Gene
  3. Kcnj8 - potassium inwardly-rectifying channel, subfamily J, member 8 Gene

Kcnj8 - potassium inwardly-rectifying channel, subfamily J, member 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: sltr; gnite; slmbr; Kir6.1; uKATP-1

基因 ID: 16523 | 基因类型: protein coding

关于 Kcnj8

功能概要

Predicted to enable several functions, including ATP binding activity; sulfonylurea receptor binding activity; and voltage-gated Potassium Channel activity. Acts upstream of or within several processes, including defense response to virus; response to exogenous dsRNA; and response to lipopolysaccharide. Located in myofibril. Is expressed in genitourinary system and heart. Used to study coronary artery disease and hypertrichotic osteochondrodysplasia Cantu type. Orthologous to human KCNJ8 (potassium inwardly rectifying channel subfamily J member 8). [provided by Alliance of Genome Resources, Apr 2022]

Kcnj8 基因产物(6)

mRNA Protein Name
NM_001330363.1 NP_001317292.1 ATP-sensitive inward rectifier potassium channel 8 isoform 1
NM_001330366.1 NP_001317295.1 ATP-sensitive inward rectifier potassium channel 8 isoform 2
NM_008428.5 NP_032454.1 ATP-sensitive inward rectifier potassium channel 8 isoform 1
NM_001330363.1 NP_001317292.1 ATP-sensitive inward rectifier potassium channel 8 isoform 1
NM_001330366.1 NP_001317295.1 ATP-sensitive inward rectifier potassium channel 8 isoform 2
NM_008428.5 NP_032454.1 ATP-sensitive inward rectifier potassium channel 8 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18001767 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within CAMKK-AMPK signaling cascade IMP
IMP: 通过突变表型推断
24498880 MGI
acts upstream of or within NLRP3 inflammasome complex assembly IDA
IDA: 通过直接分析推断
28928055 MGI
acts upstream of or within NLRP3 inflammasome complex assembly IMP
IMP: 通过突变表型推断
28928055 MGI
acts upstream of or within action potential IGI
IGI: 通过遗传相互作用推断
16501027 MGI
acts upstream of or within action potential IMP
IMP: 通过突变表型推断
21984445 MGI
acts upstream of or within adaptive immune response IMP
IMP: 通过突变表型推断
17077304 MGI
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
24498880 MGI
acts upstream of or within atrioventricular node cell differentiation IMP
IMP: 通过突变表型推断
29666184 MGI
acts upstream of or within blood vessel development IMP
IMP: 通过突变表型推断
30089727 MGI
acts upstream of or within calcium ion transmembrane transport IMP
IMP: 通过突变表型推断
28893911 MGI
acts upstream of or within cardiac pacemaker cell differentiation IMP
IMP: 通过突变表型推断
29666184 MGI
acts upstream of or within cell population proliferation IMP
IMP: 通过突变表型推断
28928055 MGI
acts upstream of or within circulatory system development IMP
IMP: 通过突变表型推断
30089727 MGI
acts upstream of or within coronary vasculature development IGI
IGI: 通过遗传相互作用推断
31821173 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
11984590 MGI
acts upstream of or within cytokine production IGI
IGI: 通过遗传相互作用推断
19166858 MGI
acts upstream of or within defense response to virus IMP
IMP: 通过突变表型推断
18026101 MGI
acts upstream of or within determination of adult lifespan IGI
IGI: 通过遗传相互作用推断
16501027 MGI
acts upstream of or within endothelin production IMP
IMP: 通过突变表型推断
17341678 MGI
acts upstream of or within establishment of cell polarity IDA
IDA: 通过直接分析推断
29540778 MGI
acts upstream of or within establishment of cell polarity IMP
IMP: 通过突变表型推断
29540778 MGI
acts upstream of or within fat cell differentiation IMP
IMP: 通过突变表型推断
26828268 MGI
acts upstream of or within fatty acid transport IMP
IMP: 通过突变表型推断
26828268 MGI
acts upstream of or within fibroblast proliferation IGI
IGI: 通过遗传相互作用推断
19166858 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
26828268 MGI
acts upstream of or within glutamate secretion, neurotransmission IGI
IGI: 通过遗传相互作用推断
17883401 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
18026101 MGI
acts upstream of or within heart morphogenesis IGI
IGI: 通过遗传相互作用推断
31821173 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
30089727 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
29540778 MGI
acts upstream of or within microglial cell activation IMP
IMP: 通过突变表型推断
29540778 MGI
acts upstream of or within nervous system process IMP
IMP: 通过突变表型推断
30315808 MGI
acts upstream of or within neuromuscular process IMP
IMP: 通过突变表型推断
17883401 MGI
acts upstream of or within p38MAPK cascade IMP
IMP: 通过突变表型推断
29540778 MGI
acts upstream of or within phloem or xylem histogenesis IMP
IMP: 通过突变表型推断
24914196 MGI
acts upstream of or within potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
28928055 MGI
acts upstream of or within protein secretion IMP
IMP: 通过突变表型推断
26828268 MGI
acts upstream of or within reactive gliosis IMP
IMP: 通过突变表型推断
30315808 MGI
acts upstream of or within regulation of blood pressure IGI
IGI: 通过遗传相互作用推断
31821173 MGI
acts upstream of or within regulation of blood pressure IMP
IMP: 通过突变表型推断
24914196 MGI
acts upstream of or within regulation of cation channel activity IGI
IGI: 通过遗传相互作用推断
31821173 MGI
acts upstream of or within regulation of heart rate IMP
IMP: 通过突变表型推断
29666184 MGI
acts upstream of or within response to ATP IMP
IMP: 通过突变表型推断
21984445 MGI
acts upstream of or within response to cytokine IMP
IMP: 通过突变表型推断
17077304 MGI
acts upstream of or within response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
30315808 MGI
acts upstream of or within response to exogenous dsRNA IMP
IMP: 通过突变表型推断
18026101 MGI
acts upstream of or within response to hypoxia IMP
IMP: 通过突变表型推断
28893911 MGI
acts upstream of or within response to insulin IMP
IMP: 通过突变表型推断
28928055 MGI
acts upstream of or within response to ischemia IMP
IMP: 通过突变表型推断
21984445 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
17077304 MGI
acts upstream of or within response to resveratrol IMP
IMP: 通过突变表型推断
24498880 MGI
acts upstream of or within response to stress IGI
IGI: 通过遗传相互作用推断
16501027 MGI
acts upstream of or within response to xenobiotic stimulus IGI
IGI: 通过遗传相互作用推断
31821173 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
11984590 MGI
acts upstream of or within synaptic assembly at neuromuscular junction IMP
IMP: 通过突变表型推断
26142302 MGI
acts upstream of or within transmission of nerve impulse IMP
IMP: 通过突变表型推断
26142302 MGI
acts upstream of or within vasculature development IMP
IMP: 通过突变表型推断
11984590 MGI
acts upstream of or within vasodilation IMP
IMP: 通过突变表型推断
11984590 MGI
acts upstream of or within ventricular cardiac muscle tissue development IGI
IGI: 通过遗传相互作用推断
16501027 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in myofibril IDA
IDA: 通过直接分析推断
16085792 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
17883401 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
17883401 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATP-sensitive inward rectifier potassium channel 8

inward rectifier K(+) channel Kir6.1

inwardly rectifier K(+) channel Kir6.1

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07150 KCNJ8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22588 Kcnj8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnj8 NCBI NCBI:3764
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