2. Gene
  3. Kif1b - kinesin family member 1B Gene

Kif1b - kinesin family member 1B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D4Mil1e; KIF1Bp130; KIF1Bp204; A530096N05Rik

基因 ID: 16561 | 基因类型: protein coding

关于 Kif1b

功能概要

Enables plus-end-directed microtubule motor activity. Involved in anterograde axonal transport; neuromuscular synaptic transmission; and neuron-neuron synaptic transmission. Acts upstream of or within mitochondrion transport along microtubule. Located in cytoplasmic vesicle membrane and mitochondrion. Part of microtubule associated complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb segment; and skeletal musculature. Used to study Charcot-Marie-Tooth disease type 2A1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2A1; carcinoma (multiple); multiple sclerosis; neuroblastoma; and pheochromocytoma. Orthologous to human KIF1B (Kinesin family member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Kif1b 基因产物(3)

mRNA Protein Name
NM_001290995.1 NP_001277924.1 kinesin-like protein KIF1B isoform c
NM_008441.2 NP_032467.2 kinesin-like protein KIF1B isoform a
NM_207682.2 NP_997565.2 kinesin-like protein KIF1B isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables plus-end-directed microtubule motor activity IDA
IDA: 通过直接分析推断
7528108 MGI
enables plus-end-directed microtubule motor activity IMP
IMP: 通过突变表型推断
11389829 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15975910 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterograde synaptic vesicle transport IMP
IMP: 通过突变表型推断
11389829 MGI
acts upstream of or within mitochondrion transport along microtubule IDA
IDA: 通过直接分析推断
7528108 MGI
involved in mitochondrion transport along microtubule IDA
IDA: 通过直接分析推断
7528108 MGI
involved in neuromuscular synaptic transmission IMP
IMP: 通过突变表型推断
11389829 MGI
involved in neuron-neuron synaptic transmission IMP
IMP: 通过突变表型推断
11389829 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
7528108 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
22945799 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
22945799 MGI
NOT located in synaptic membrane IDA
IDA: 通过直接分析推断
11389829 MGI
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
11389829 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kinesin-like protein KIF1B

N-3 kinesin

kinesin heavy chain member 1B

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07270 KIF1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21616 Kif1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28134 Kif1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kif1b NCBI NCBI:23095
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