2. Gene
  3. Krt19 - keratin 19 Gene

Krt19 - keratin 19 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: K19; CK-19; EndoC; Krt1-19; Krt-1.19

基因 ID: 16669 | 基因类型: protein coding

关于 Krt19

功能概要

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Krt19 基因产物(2)

mRNA Protein Name
NM_001313963.1 NP_001300892.1 keratin, type I cytoskeletal 19 isoform 2
NM_008471.3 NP_032497.1 keratin, type I cytoskeletal 19 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19321664 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Notch signaling pathway IDA
IDA: 通过直接分析推断
25446530 MGI
acts upstream of or within cell differentiation involved in embryonic placenta development IGI
IGI: 通过遗传相互作用推断
11062258 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
15247274 MGI
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
25232867 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
15247274 MGI
located in terminal web IDA
IDA: 通过直接分析推断
19321664 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

keratin, type I cytoskeletal 19

cytokeratin 19

keratin complex 1, acidic, gene 19

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07442 KRT19 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16276 Krt19 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25946 Krt19 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt19 NCBI NCBI:3880
Canis familiaris Krt19 NCBI NCBI:100685481
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