1. Gene
  2. Krt8 - keratin 8 Gene

Krt8 - keratin 8 Gene

种属: Mus musculus

同用名: K8; Card2; EndoA; Krt2-8; Krt-2.8

基因 ID: 16691 | 基因类型: protein coding

关于 Krt8

功能概要

Predicted to enable scaffold protein binding activity. Acts upstream of or within several processes, including cell differentiation involved in embryonic placenta development; cell surface receptor signaling pathway; and hepatocyte apoptotic process. Located in several cellular components, including Z disc; apicolateral plasma membrane; and sarcolemma. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT8 (keratin 8). [provided by Alliance of Genome Resources, Apr 2022]

Krt8 基因产物(1)

mRNA Protein Name
NM_031170.2 NP_112447.2 keratin, type II cytoskeletal 8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10747083 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
15247274 MGI
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
25232867 MGI
located in cell periphery IDA
IDA: 通过直接分析推断
19487454 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
23266329 MGI
located in intermediate filament IDA
IDA: 通过直接分析推断
10747083 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
15247274 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

keratin, type II cytoskeletal 8

CK-8

cytokeratin endo A

cytokeratin-8

keratin complex 2, basic, gene 8

type-II keratin Kb8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt8 NCBI NCBI:3856