1. Gene
  2. Lamb1 - laminin B1 Gene

Lamb1 - laminin B1 Gene

种属: Mus musculus

同用名: Lamb-1; Lamb1-1; D130003D08Rik

基因 ID: 16777 | 基因类型: protein coding

关于 Lamb1

功能概要

Enables enzyme binding activity; glycosphingolipid binding activity; and Integrin binding activity. Involved in negative regulation of cell adhesion. Acts upstream of or within cell migration; embryo implantation; and neuron projection development. Located in basement membrane; nucleus; and perinuclear region of cytoplasm. Part of laminin-1 complex and laminin-10 complex. Is expressed in several structures, including alimentary system; extraembryonic component; eye; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in autistic disorder and lissencephaly 5. Orthologous to human LAMB1 (laminin subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Lamb1 基因产物(1)

mRNA Protein Name
NM_008482.3 NP_032508.3 laminin subunit beta-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
15474030 MGI
enables glycosphingolipid binding IDA
IDA: 通过直接分析推断
19118221 MGI
enables integrin binding IMP
IMP: 通过突变表型推断
9004048 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7639691 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell migration IMP
IMP: 通过突变表型推断
9004048 MGI
acts upstream of or within embryo implantation IMP
IMP: 通过突变表型推断
15102706 MGI
involved in negative regulation of cell adhesion IDA
IDA: 通过直接分析推断
7639691 MGI
acts upstream of or within neuron projection development IDA
IDA: 通过直接分析推断
19118221 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
1292752 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
16554364 MGI
part of laminin complex IDA
IDA: 通过直接分析推断
8034675 MGI
part of laminin-1 complex IDA
IDA: 通过直接分析推断
9264260 MGI
part of laminin-10 complex IPI
IPI: 通过物理相互作用推断
9299121 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10444590 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15207330 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

laminin subunit beta-1

laminin B1 chain

laminin B1 subunit 1

laminin-1 subunit beta

laminin-10 subunit beta

laminin-111

laminin-12 subunit beta

laminin-2 subunit beta

laminin-6 subunit beta

laminin-8 subunit beta

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lamb1 NCBI NCBI:3912