1. Gene
  2. QSOX2 - quiescin sulfhydryl oxidase 2 Gene

QSOX2 - quiescin sulfhydryl oxidase 2 Gene

中文名称:静止素巯基氧化酶 2

种属: Homo sapiens

同用名: SOXN; QSCN6L1

基因 ID: 169714 | 基因类型: protein coding

关于 QSOX2

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,206,333-136,245,812 (from NCBI)

This gene has 2 transcripts (splice variants), 199 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 8.6), spleen (RPKM 7.1) and 25 other tissues.

功能概要

QSOX2 是巯基氧化酶/quiescin-6 (Q6) 家族 (QSOX1; MIM 603120) 的成员,可调节神经母细胞瘤细胞对 IFN-γ (IFNG; MIM 147570) 诱导的细胞死亡的敏感性 (Wittke 等人,2003 年) [PubMed 14633699]) .[OMIM 提供,2009 年 6 月]

QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009]

QSOX2 基因产物(1)

mRNA Protein Name
NM_181701.4 NP_859052.3 sulfhydryl oxidase 2 precursor

QSOX2 蛋白结构

Thioredoxin

Thioredoxin: Thioredoxin (74 - 150)

Evr1_Alr

Evr1_Alr: Erv1 / Alr family (430 - 532)

  • 0
  • 200
  • 400
  • 600
  • 698 a.a.
蛋白主名 其他名称

sulfhydryl oxidase 2

neuroblastoma-derived sulfhydryl oxidase

关联疾病

疾病名称 别名
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Deafness, Autosomal Recessive 33

DFNB33

Autosomal Recessive Nonsyndromic Deafness 33

Autosomal Recessive Deafness 33

Deafness, Autosomal Dominant 50

DFNA50

Autosomal Dominant Nonsyndromic Deafness 50

Autosomal Dominant Deafness 50

Deafness, Autosomal Dominant, Type 50

Deafness, Autosomal Recessive 79

DFNB79

Autosomal Recessive Nonsyndromic Deafness 79

Autosomal Recessive Deafness 79

Deafness, Autosomal Recessive, 79

Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 79

Deafness, Autosomal Recessive, Type 79

Pituitary Adenoma 5, Multiple Types

PITA5

Pituitary Adenoma 5

{Pituitary Adenoma 5, Multiple Types}

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus QSOX2 RGD RGD:1584720
Felis catus QSOX2 VGNC VGNC:64462
Mus musculus QSOX2 MGD MGI:2387194
Macaca mulatta QSOX2 VGNC VGNC:76568
Canis familiaris QSOX2 VGNC VGNC:45239
Bos taurus QSOX2 VGNC VGNC:33606