2. Gene
  3. Havcr2 - hepatitis A virus cellular receptor 2 Gene

Havcr2 - hepatitis A virus cellular receptor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tim3; TIM-3; Timd3

基因 ID: 171285 | 基因类型: protein coding

关于 Havcr2

功能概要

Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and Toll-like Receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Havcr2 基因产物(1)

mRNA Protein Name
NM_134250.2 NP_599011.2 hepatitis A virus cellular receptor 2 homolog precursor
蛋白主名 其他名称

hepatitis A virus cellular receptor 2 homolog

HAVcr-2

T-cell immunoglobulin and mucin domain containing 3

T-cell immunoglobulin and mucin domain-containing protein 3

T-cell immunoglobulin mucin receptor 3

T-cell membrane protein 3

TIMD-3

Havcr2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Havcr2 Q8VIM0 Lgals9 Mus musculus O08573-2
Pull Down
16286920
种属内
Havcr2 Q8VIM0 Hmgb1 Mus musculus P63158
Confocal
22842346
种属内
Havcr2 Q8VIM0 Hmgb1 Mus musculus P63158
ELISA
22842346
种属内
Havcr2 Q8VIM0 Hmgb1 Mus musculus P63158
Anti Tag CoIP
22842346
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Havcr2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70826 TIM-3/HAVCR2 Protein, Mouse (HEK293, Fc) Q8VIM0-1 (R20-R191) ≥95%
HY-P71995 TIM-3/HAVCR2 Protein, Mouse (HEK 293, hFc) Q8VIM0-1 (R20-R191) ≥95%
HY-P72448 TIM-3/HAVCR2 Protein, Mouse (HEK293, His) Q8VIM0-1 (R20-R191) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P990085 Verzistobart Inhibitor / Phase 2
HY-P990701 Lomvastomig / Phase 2
HY-P990716 Sabestomig / Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06022 HAVCR2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17115 Havcr2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23560 Havcr2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991395 TQB2618 Inhibitor / 否
HY-P991396 LY-3321367 Inhibitor / 否
HY-P991397 Sym023 Inhibitor / 否
HY-P991449 LY3415244 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Havcr2 NCBI NCBI:84868
Canis familiaris Havcr2 NCBI NCBI:479318
Macaca fascicularis Havcr2 NCBI NCBI:102141722
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