1. Gene
  2. Havcr2 - hepatitis A virus cellular receptor 2 Gene

Havcr2 - hepatitis A virus cellular receptor 2 Gene

种属: Mus musculus

同用名: Tim3; TIM-3; Timd3

基因 ID: 171285 | 基因类型: protein coding

关于 Havcr2

功能概要

Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and Toll-like Receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Havcr2 基因产物(1)

mRNA Protein Name
NM_134250.2 NP_599011.2 hepatitis A virus cellular receptor 2 homolog precursor
蛋白主名 其他名称

hepatitis A virus cellular receptor 2 homolog

HAVcr-2

T-cell immunoglobulin and mucin domain containing 3

T-cell immunoglobulin and mucin domain-containing protein 3

T-cell immunoglobulin mucin receptor 3

T-cell membrane protein 3

TIMD-3

Havcr2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Havcr2 Q8VIM0 Lgals9 Mus musculus O08573-2 16286920
种属内
Havcr2 Q8VIM0 Hmgb1 Mus musculus P63158 22842346
种属内
Havcr2 Q8VIM0 Hmgb1 Mus musculus P63158 22842346
种属内
Havcr2 Q8VIM0 Hmgb1 Mus musculus P63158 22842346
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Havcr2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70826 TIM-3/HAVCR2 Protein, Mouse (HEK293, Fc) Q8VIM0-1 (R20-R191) ≥95%
HY-P71995 TIM-3/HAVCR2 Protein, Mouse (HEK 293, hFc) Q8VIM0-1 (R20-R191) ≥95%
HY-P72448 TIM-3/HAVCR2 Protein, Mouse (HEK293, His) Q8VIM0-1 (R20-R191) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Havcr2 NCBI NCBI:84868
Canis familiaris Havcr2 NCBI NCBI:479318
Macaca fascicularis Havcr2 NCBI NCBI:102141722