2. Gene
  3. Mef2a - myocyte enhancer factor 2A Gene

Mef2a - myocyte enhancer factor 2A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: A430079H05Rik

基因 ID: 17258 | 基因类型: protein coding

关于 Mef2a

功能概要

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including mitochondrion organization; positive regulation of macromolecule metabolic process; and ventricular cardiac myofibril assembly. Acts upstream of or within positive regulation of glucose import and positive regulation of transcription, DNA-templated. Located in chromatin and nucleus. Is expressed in several structures, including brain; cardiovascular system; embryo mesenchyme; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A). [provided by Alliance of Genome Resources, Apr 2022]

Mef2a 基因产物(7)

mRNA Protein Name
NM_001033713.2 NP_001028885.1 myocyte-specific enhancer factor 2A isoform a
NM_001291191.2 NP_001278120.1 myocyte-specific enhancer factor 2A isoform b
NM_001291192.1 NP_001278121.1 myocyte-specific enhancer factor 2A isoform b
NM_001291195.1 NP_001278124.1 myocyte-specific enhancer factor 2A isoform c
NM_001291196.1 NP_001278125.1 myocyte-specific enhancer factor 2A isoform d
NM_001357324.1 NP_001344253.1 myocyte-specific enhancer factor 2A isoform e
NM_001357325.1 NP_001344254.1 myocyte-specific enhancer factor 2A isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
9738004 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
16407236 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
9738004 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
21379568 MGI
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
11160896 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9430690 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
16407236 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7973707 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
17785444 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8096811 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac conduction IMP
IMP: 通过突变表型推断
12379849 MGI
involved in mitochondrial genome maintenance IMP
IMP: 通过突变表型推断
12379849 MGI
involved in mitochondrion distribution IMP
IMP: 通过突变表型推断
12379849 MGI
acts upstream of or within positive regulation of D-glucose import IDA
IDA: 通过直接分析推断
12097321 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12097321 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
29606596 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16407236 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
8900141 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
9738004 MGI
involved in ventricular cardiac myofibril assembly IMP
IMP: 通过突变表型推断
12379849 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
20833138 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9013788 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myocyte-specific enhancer factor 2A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08309 MEF2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19713 Mef2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26209 Mef2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mef2a NCBI NCBI:4205
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