1. Gene
  2. Mllt10 - myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 Gene

Mllt10 - myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 Gene

种属: Mus musculus

同用名: Af10; mKIAA4140; B130021D15Rik; D630001B22Rik

基因 ID: 17354 | 基因类型: protein coding

关于 Mllt10

功能概要

Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; early conceptus; genitourinary system; limb; and maxillary process. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Orthologous to human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor). [provided by Alliance of Genome Resources, Apr 2022]

Mllt10 基因产物(3)

mRNA Protein Name
NM_001252560.1 NP_001239489.1 protein AF-10 isoform 1
NM_001252561.1 NP_001239490.1 protein AF-10 isoform 2
NM_010804.4 NP_034934.2 protein AF-10 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21103407 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein AF-10

myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

translocated to, 10

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mllt10 NCBI NCBI:8028