2. Gene
  3. Map1a - microtubule-associated protein 1 A Gene

Map1a - microtubule-associated protein 1 A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mtap1; moth1; Mtap-1; Mtap1a; 6330416M19Rik

基因 ID: 17754 | 基因类型: protein coding

关于 Map1a

功能概要

Enables cytoskeletal anchor activity; cytoskeletal protein binding activity; and ionotropic glutamate receptor binding activity. Involved in several processes, including axo-dendritic protein transport; learning or memory; and negative regulation of protein localization to microtubule. Acts upstream of or within photoreceptor cell maintenance and sensory perception of sound. Located in several cellular components, including axon initial segment; dendritic microtubule; and photoreceptor outer segment. Is expressed in cerebral cortex marginal zone; cortical plate; cortical subplate; and spinal cord. Orthologous to human MAP1A (microtubule associated protein 1A). [provided by Alliance of Genome Resources, Apr 2022]

Map1a 基因产物(2)

mRNA Protein Name
NM_001173506.1 NP_001166977.1 microtubule-associated protein 1A isoform 2
NM_032393.2 NP_115769.1 microtubule-associated protein 1A isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
26609151 MGI
enables cytoskeletal anchor activity IDA
IDA: 通过直接分析推断
26609151 MGI
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
26609151 MGI
enables microtubule binding IDA
IDA: 通过直接分析推断
17360631 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11925566 MGI
enables tubulin binding IDA
IDA: 通过直接分析推断
26609151 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterograde axonal protein transport IGI
IGI: 通过遗传相互作用推断
26609151 MGI
involved in associative learning IMP
IMP: 通过突变表型推断
26609151 MGI
involved in memory IMP
IMP: 通过突变表型推断
26609151 MGI
involved in microtubule cytoskeleton organization IMP
IMP: 通过突变表型推断
25788676 MGI
involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
26609151 MGI
involved in negative regulation of protein localization to microtubule IMP
IMP: 通过突变表型推断
25788676 MGI
involved in neuron cellular homeostasis IMP
IMP: 通过突变表型推断
25788676 MGI
involved in neuron projection maintenance IMP
IMP: 通过突变表型推断
25788676 MGI
acts upstream of or within photoreceptor cell maintenance IGI
IGI: 通过遗传相互作用推断
22323461 MGI
involved in positive regulation of protein localization IMP
IMP: 通过突变表型推断
26609151 MGI
involved in positive regulation of protein localization to cell surface IMP
IMP: 通过突变表型推断
26609151 MGI
involved in regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
26609151 MGI
involved in retrograde axonal protein transport IGI
IGI: 通过遗传相互作用推断
26609151 MGI
acts upstream of or within sensory perception of sound IDA
IDA: 通过直接分析推断
11925566 MGI
involved in voluntary musculoskeletal movement IMP
IMP: 通过突变表型推断
25788676 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon initial segment IDA
IDA: 通过直接分析推断
25788676 MGI
located in cytosol IDA
IDA: 通过直接分析推断
11925566 MGI
located in dendrite IDA
IDA: 通过直接分析推断
25788676 MGI
located in dendritic microtubule IDA
IDA: 通过直接分析推断
25788676 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
25788676 MGI
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
24664738 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
17114649 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

microtubule-associated protein 1A

MAP-1A

modifier of tubby hearing 1

short MAP1A

short microtubule-associated protein 1A

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08026 MAP1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08348 METAP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18394 Map1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24875 Map1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map1a NCBI NCBI:4130
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