2. Gene
  3. Nrg3 - neuregulin 3 Gene

Nrg3 - neuregulin 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ska

基因 ID: 18183 | 基因类型: protein coding

关于 Nrg3

功能概要

Enables chemorepellent activity. Acts upstream of or within several processes, including intracellular signal transduction; mammary placode formation; and regulation of cell migration. Predicted to be located in extracellular region and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space and glutamatergic synapse. Is expressed in several structures, including epidermis; mammary gland primordium; nervous system; testis; and trunk mesenchyme. Used to study schizophrenia. Orthologous to human NRG3 (neuregulin 3). [provided by Alliance of Genome Resources, Apr 2022]

Nrg3 基因产物(3)

mRNA Protein Name
NM_001190187.1 NP_001177116.1 pro-neuregulin-3, membrane-bound isoform isoform 2
NM_001190188.1 NP_001177117.1 pro-neuregulin-3, membrane-bound isoform isoform 3
NM_008734.3 NP_032760.1 pro-neuregulin-3, membrane-bound isoform isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemorepellent activity IDA
IDA: 通过直接分析推断
22376909 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9275162 MGI
enables receptor ligand activity IPI
IPI: 通过物理相互作用推断
9275162 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERBB4 signaling pathway IPI
IPI: 通过物理相互作用推断
9275162 MGI
involved in ERBB4-ERBB4 signaling pathway IPI
IPI: 通过物理相互作用推断
9275162 MGI
acts upstream of or within chemorepulsion involved in interneuron migration from the subpallium to the cortex IMP
IMP: 通过突变表型推断
22376909 MGI
acts upstream of or within intracellular signal transduction IDA
IDA: 通过直接分析推断
9275162 MGI
acts upstream of or within mammary gland development IDA
IDA: 通过直接分析推断
16140987 MGI
acts upstream of or within mammary gland development IMP
IMP: 通过突变表型推断
16140987 MGI
acts upstream of or within mammary placode formation IMP
IMP: 通过突变表型推断
10723730 MGI
acts upstream of or within negative regulation of neuron migration IDA
IDA: 通过直接分析推断
22376909 MGI
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
10723730 MGI
involved in synapse assembly IDA
IDA: 通过直接分析推断
30049711 MGI
involved in synapse assembly IMP
IMP: 通过突变表型推断
30049711 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extracellular space IDA
IDA: 通过直接分析推断
30049711 MGI
is active in extracellular space IPI
IPI: 通过物理相互作用推断
9275162 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
30049711 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
30049711 MGI
is active in synapse IDA
IDA: 通过直接分析推断
33320083 MGI
is active in synapse IMP
IMP: 通过突变表型推断
33320083 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pro-neuregulin-3, membrane-bound isoform

pro-NRG3

scaramanga

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09568 NRG3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174565 Human NRG3 mRNA / 否
HY-RS17691 Nrg3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24153 Nrg3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nrg3 NCBI NCBI:10718
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