1. Gene
  2. Pemt - phosphatidylethanolamine N-methyltransferase Gene

Pemt - phosphatidylethanolamine N-methyltransferase Gene

种属: Mus musculus

同用名: PLMT; PEAMT; PEMT2; Pempt; Pempt2

基因 ID: 18618 | 基因类型: protein coding

关于 Pemt

功能概要

Enables S-adenosylmethionine-dependent methyltransferase activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within blastocyst hatching and sphingomyelin biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; early conceptus; liver; lung; and secondary oocyte. Orthologous to human PEMT (phosphatidylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Pemt 基因产物(5)

mRNA Protein Name
NM_001290011.1 NP_001276940.1 phosphatidylethanolamine N-methyltransferase isoform a
NM_001290012.1 NP_001276941.1 phosphatidylethanolamine N-methyltransferase isoform b
NM_001290013.1 NP_001276942.1 phosphatidylethanolamine N-methyltransferase isoform b
NM_001290014.1 NP_001276943.1 phosphatidylethanolamine N-methyltransferase isoform c
NM_008819.3 NP_032845.2 phosphatidylethanolamine N-methyltransferase isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables S-adenosylmethionine-dependent methyltransferase activity IMP
IMP: 通过突变表型推断
25667419 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
27869233 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
26113536 MGI
acts upstream of or within sphingomyelin biosynthetic process IMP
IMP: 通过突变表型推断
25667419 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
12072432 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylethanolamine N-methyltransferase

phospholipid methyltransferase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pemt NCBI NCBI:10400
Macaca fascicularis Pemt NCBI NCBI:102139053