2. Gene
  3. Pfkm - phosphofructokinase, muscle Gene

Pfkm - phosphofructokinase, muscle Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pfk4; Pfka; Pfkx; PFK-A; PFK-M; Pfk-4; ATP-PFK

基因 ID: 18642 | 基因类型: protein coding

关于 Pfkm

功能概要

Enables 6-phosphofructokinase activity and identical protein binding activity. Acts upstream of or within several processes, including glycogen catabolic process; glycolytic process through glucose-6-phosphate; and positive regulation of Insulin secretion. Located in cytosol and sperm principal piece. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and musculoskeletal system. Used to study glycogen storage disease VII. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKM (phosphofructokinase, muscle). [provided by Alliance of Genome Resources, Apr 2022]

Pfkm 基因产物(4)

mRNA Protein Name
NM_001163487.1 NP_001156959.1 ATP-dependent 6-phosphofructokinase, muscle type
NM_001163488.1 NP_001156960.1 ATP-dependent 6-phosphofructokinase, muscle type
NM_001357688.1 NP_001344617.1 ATP-dependent 6-phosphofructokinase, muscle type
NM_021514.4 NP_067489.3 ATP-dependent 6-phosphofructokinase, muscle type
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 6-phosphofructokinase activity IDA
IDA: 通过直接分析推断
2521854 MGI
enables 6-phosphofructokinase activity IMP
IMP: 通过突变表型推断
17595219 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
19889946 MGI
enables phosphofructokinase activity IDA
IDA: 通过直接分析推断
11785984 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in canonical glycolysis IDA
IDA: 通过直接分析推断
4275392 MGI
involved in canonical glycolysis IGI
IGI: 通过遗传相互作用推断
27760309 MGI
acts upstream of or within canonical glycolysis IMP
IMP: 通过突变表型推断
19696889 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
17595219 MGI
acts upstream of or within glycogen catabolic process IMP
IMP: 通过突变表型推断
19696889 MGI
acts upstream of or within glycolysis from storage polysaccharide through glucose-1-phosphate IMP
IMP: 通过突变表型推断
19696889 MGI
acts upstream of or within glycolytic process through fructose-6-phosphate IDA
IDA: 通过直接分析推断
2521854 MGI
involved in glycolytic process through fructose-6-phosphate IDA
IDA: 通过直接分析推断
19889946 MGI
acts upstream of or within glycolytic process through fructose-6-phosphate IMP
IMP: 通过突变表型推断
17595219 MGI
acts upstream of or within positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
17595219 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
2521854 MGI
located in cytosol IDA
IDA: 通过直接分析推断
2521854 MGI
located in sperm principal piece IDA
IDA: 通过直接分析推断
19889946 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATP-dependent 6-phosphofructokinase, muscle type

6-phosphofructokinase type A

6-phosphofructokinase, muscle type

phosphofructo-1-kinase isozyme A

phosphofructokinase 1

phosphofructokinase 4

phosphofructokinase M variant 3/4

phosphofructokinase, polypeptide X

phosphofructokinase-1 A isozyme

phosp

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS18964 Pfkm Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10366 PFKM Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25454 Pfkm Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pfkm NCBI NCBI:5213
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