2. Gene
  3. Pip4k2a - phosphatidylinositol-5-phosphate 4-kinase, type II, alpha Gene

Pip4k2a - phosphatidylinositol-5-phosphate 4-kinase, type II, alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pip5k2a

基因 ID: 18718 | 基因类型: protein coding

关于 Pip4k2a

功能概要

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; and protein homodimerization activity. Involved in autophagosome-lysosome fusion; megakaryocyte development; and regulation of Autophagy. Located in lysosome. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and nose. Orthologous to human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pip4k2a 基因产物(5)

mRNA Protein Name
NM_001355146.1 NP_001342075.1 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 2
NM_001355147.1 NP_001342076.1 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 3
NM_001355148.1 NP_001342077.1 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 4
NM_001355149.1 NP_001342078.1 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 5
NM_008845.4 NP_032871.3 phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26760201 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagosome-lysosome fusion IMP
IMP: 通过突变表型推断
29727621 MGI
involved in megakaryocyte development IMP
IMP: 通过突变表型推断
16434494 MGI
involved in regulation of autophagy IMP
IMP: 通过突变表型推断
29727621 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in lysosome IDA
IDA: 通过直接分析推断
29727621 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha

PI(5)P 4-kinase type II alpha

PI5P4Kalpha

PIP4KII-alpha

diphosphoinositide kinase 2-alpha

phosphatidylinositol-4-phosphate 5-kinase, type II, alpha

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139868 BAY-091 Inhibitor 98.45% 否
HY-136310 PIP4K-IN-a131 Inhibitor 99.42% 否
HY-RS10562 PIP4K2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19282 Pip4k2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25772 Pip4k2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pip4k2a NCBI NCBI:5305
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