2. Gene
  3. Mfn1 - mitofusin 1 Gene

Mfn1 - mitofusin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Fzo1b

基因 ID: 192647 | 基因类型: protein coding

关于 Mfn1

功能概要

Enables identical protein binding activity. Involved in several processes, including cellular response to decreased oxygen levels; regulation of mitochondrion organization; and response to glucocorticoid. Located in mitochondrial inner membrane and mitochondrial outer membrane. Biomarker of several diseases, including adult respiratory distress syndrome; dental fluorosis; kidney failure (multiple); pulmonary hypertension; and status epilepticus. Orthologous to human MFN1 (mitofusin 1). [provided by Alliance of Genome Resources, Apr 2022]

Mfn1 基因产物(1)

mRNA Protein Name
NM_138976.2 NP_620432.2 mitofusin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
14561718 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
22703557 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
28518143 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
23658809 RGD
involved in intracellular distribution of mitochondria IMP
IMP: 通过突变表型推断
19605646 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
14592431 RGD
involved in mitochondrion organization IMP
IMP: 通过突变表型推断
19605646 RGD
involved in negative regulation of mitochondrial fission IMP
IMP: 通过突变表型推断
18832378 RGD
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
19605646 RGD
involved in positive regulation of mitochondrial fusion IMP
IMP: 通过突变表型推断
24751540 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
25308841 RGD
involved in response to corticosterone IEP
IEP: 通过表达模式推断
22244747 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
26513006 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
24751540 RGD
involved in response to flavonoid IEP
IEP: 通过表达模式推断
24637344 RGD
involved in response to fluoride IEP
IEP: 通过表达模式推断
24958380 RGD
involved in response to hypobaric hypoxia IEP
IEP: 通过表达模式推断
24637344 RGD
involved in response to manganese ion IEP
IEP: 通过表达模式推断
15589972 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
19716857 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
25336449 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
27801955 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
27801955 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitofusin-1

mitochondrial transmembrane GTPase FZO1B

transmembrane GTPase MFN1

Mfn1 抗体

目录号 产品名 应用 反应物种
HY-P80751 Mitofusin 1 Antibody (YA291) WB, IP Mouse, Rat, Hamster

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150031 MFI8 Inhibitor 99.67% 否
HY-126124 AP39 96.35% 否
HY-P3429A SAMβA TFA Inhibitor 99.13% 否
HY-P3429 SAMβA Inhibitor / 否
HY-P5891 TAT-SAMβA Antagonist / 否
HY-RS08383 MFN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17749 Mfn1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24215 Mfn1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mfn1 NCBI NCBI:55669
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