2. Gene
  3. Ptprs - protein tyrosine phosphatase, receptor type, S Gene

Ptprs - protein tyrosine phosphatase, receptor type, S Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PTP; Ptpt9; PTP-NU3; PTPNU-3; R-PTP-S; PTPsigma; RPTPsigma

基因 ID: 19280 | 基因类型: protein coding

关于 Ptprs

功能概要

Enables chondroitin sulfate binding activity; heparin binding activity; and protein tyrosine Phosphatase activity. Involved in several processes, including negative regulation of neuron projection development; peptidyl-tyrosine dephosphorylation; and regulation of postsynaptic density assembly. Acts upstream of or within central nervous system development and establishment of endothelial intestinal barrier. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Is integral component of presynaptic membrane. Is expressed in several structures, including adipose tissue; genitourinary system; gut; nervous system; and sensory organ. Orthologous to human PTPRS (protein tyrosine Phosphatase receptor type S). [provided by Alliance of Genome Resources, Apr 2022]

Ptprs 基因产物(4)

mRNA Protein Name
NM_001252453.1 NP_001239382.1 receptor-type tyrosine-protein phosphatase S isoform 2 precursor
NM_001252455.1 NP_001239384.1 receptor-type tyrosine-protein phosphatase S isoform 3 precursor
NM_001252456.1 NP_001239385.1 receptor-type tyrosine-protein phosphatase S isoform 2 precursor
NM_011218.2 NP_035348.2 receptor-type tyrosine-protein phosphatase S isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chondroitin sulfate binding IDA
IDA: 通过直接分析推断
22406547 MGI
enables heparin binding IDA
IDA: 通过直接分析推断
22406547 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24385580 MGI
enables protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
7529177 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cerebellum development IMP
IMP: 通过突变表型推断
15842738 MGI
acts upstream of or within cerebral cortex development IMP
IMP: 通过突变表型推断
15842738 MGI
acts upstream of or within corpus callosum development IMP
IMP: 通过突变表型推断
15842738 MGI
acts upstream of or within establishment of endothelial intestinal barrier IMP
IMP: 通过突变表型推断
24385580 MGI
acts upstream of or within hippocampus development IMP
IMP: 通过突变表型推断
15842738 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
22519304 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
22519304 MGI
involved in negative regulation of axon extension IMP
IMP: 通过突变表型推断
19780196 MGI
involved in negative regulation of axon regeneration IMP
IMP: 通过突变表型推断
19780196 MGI
involved in negative regulation of collateral sprouting IMP
IMP: 通过突变表型推断
22519304 MGI
involved in negative regulation of dendritic spine development IMP
IMP: 通过突变表型推断
22519304 MGI
involved in negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
22406547 MGI
involved in peptidyl-tyrosine dephosphorylation IDA
IDA: 通过直接分析推断
7529177 MGI
acts upstream of or within peptidyl-tyrosine dephosphorylation IMP
IMP: 通过突变表型推断
24385580 MGI
involved in regulation of postsynaptic density assembly IDA
IDA: 通过直接分析推断
21262467 MGI
involved in regulation of postsynaptic density assembly IMP
IMP: 通过突变表型推断
21262467 MGI
acts upstream of or within spinal cord development IMP
IMP: 通过突变表型推断
15842738 MGI
involved in synapse organization IDA
IDA: 通过直接分析推断
22519304 MGI
involved in synapse organization IMP
IMP: 通过突变表型推断
22519304 MGI
involved in trans-synaptic signaling IDA
IDA: 通过直接分析推断
32142410 MGI
involved in trans-synaptic signaling IMP
IMP: 通过突变表型推断
32142410 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
22519304 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
22519304 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21262467 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
21262467 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
26231120 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
21262467 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase S

R-PTP-sigma

Receptor-type tyrosine-protein phosphatase sigma

tissue-specific protein tyrosine phosphatase

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11449 PTPRS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21709 Ptprs Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprs NCBI NCBI:5802
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