2. Gene
  3. Rad50 - RAD50 double strand break repair protein Gene

Rad50 - RAD50 double strand break repair protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mrell; Rad50l

基因 ID: 19360 | 基因类型: protein coding

关于 Rad50

功能概要

Predicted to enable DNA binding activity; identical protein binding activity; and protein-macromolecule adaptor activity. Predicted to contribute to 3'-5' exonuclease activity; DNA helicase activity; and single-stranded DNA endodeoxyribonuclease activity. Acts upstream of or within chromosome organization involved in meiotic cell cycle and regulation of mitotic cell cycle. Located in pronucleus. Is expressed in several structures, including aorta; hemolymphoid system gland; liver; lung; and testis. Human ortholog(s) of this gene implicated in transitional cell carcinoma. Orthologous to human RAD50 (RAD50 double strand break repair protein). [provided by Alliance of Genome Resources, Apr 2022]

Rad50 基因产物(1)

mRNA Protein Name
NM_009012.2 NP_033038.2 DNA repair protein RAD50
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30017584 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chromosome organization IMP
IMP: 通过突变表型推断
19001091 MGI
acts upstream of or within chromosome organization involved in meiotic cell cycle IMP
IMP: 通过突变表型推断
19001091 MGI
acts upstream of or within regulation of mitotic cell cycle IMP
IMP: 通过突变表型推断
19001091 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Mre11 complex IDA
IDA: 通过直接分析推断
18854157 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17982445 MGI
located in pronucleus IDA
IDA: 通过直接分析推断
17982445 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA repair protein RAD50

RAD50 homolog

mRad50

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117693 (E/Z)-Mirin Inhibitor 99.22% 否
HY-19959 Mirin 99.63% 否
HY-149972 Antitumor agent-96 Inducer / 否
HY-RS11602 RAD50 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18404 Rad50 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24885 Rad50 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rad50 NCBI NCBI:10111
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