1. Gene
  2. ENDOG - endonuclease G Gene

ENDOG - endonuclease G Gene

中文名称:核酸内切酶 G

种属: Homo sapiens

基因 ID: 2021 | 基因类型: protein coding

关于 ENDOG

Cytogenetic location: 9q34.11 Genomic coordinates (GRCh38): 9:128,818,500-128,822,676 (from NCBI)

This gene has 1 transcript (splice variant), 180 orthologues and 1 paralogue. Ubiquitous expression in kidney (RPKM 10.6), prostate (RPKM 9.4) and 25 other tissues.

功能概要

由该基因编码的蛋白质是一种核编码的核酸内切酶,位于线粒体中。编码的蛋白质广泛分布于动物中,并在 GC 道切割 DNA。这种蛋白质能够产生 DNA 聚合酶 γ 启动线粒体 DNA 复制所需的 RNA 引物。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among Animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008]

ENDOG 基因产物(1)

mRNA Protein Name
NM_004435.2 NP_004426.2 endonuclease G, mitochondrial precursor

ENDOG 蛋白结构

Endonuclease_NS

Endonuclease_NS: DNA/RNA non-specific endonuclease (78 - 282)

  • 0
  • 100
  • 200
  • 297 a.a.
蛋白主名 其他名称

endonuclease G, mitochondrial

endo G

关联疾病

疾病名称 别名
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus ENDOG VGNC VGNC:61859
Bos taurus ENDOG VGNC VGNC:28491
Mus musculus ENDOG MGD MGI:1261433
Macaca mulatta ENDOG VGNC VGNC:72218
Rattus norvegicus ENDOG RGD RGD:1310763
Canis familiaris ENDOG VGNC VGNC:40360
Others ENDOG NCBI