1. Gene
  2. Siah2 - siah E3 ubiquitin protein ligase 2 Gene

Siah2 - siah E3 ubiquitin protein ligase 2 Gene

种属: Mus musculus

同用名: Sinh2

基因 ID: 20439 | 基因类型: protein coding

关于 Siah2

功能概要

Enables ubiquitin protein Ligase activity. Involved in regulation of circadian rhythm and ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including early endosome; neuronal cell body; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; cranium; gonad; hemolymphoid system gland; and sensory organ. Orthologous to human SIAH2 (siah E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Siah2 基因产物(1)

mRNA Protein Name
NM_009174.3 NP_033200.2 E3 ubiquitin-protein ligase SIAH2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18323779 MGI
enables ubiquitin protein ligase activity IMP
IMP: 通过突变表型推断
26392558 MGI
enables ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
26070566 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of circadian rhythm IMP
IMP: 通过突变表型推断
26392558 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
26070566 MGI
involved in ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
26392558 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase SIAH2

RING-type E3 ubiquitin transferase SIAH2

mSiah2

seven in absentia 2

seven in absentia homolog 2

siah-2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Siah2 NCBI NCBI:6478