2. Gene
  3. Slc22a5 - solute carrier family 22 (organic cation transporter), member 5 Gene

Slc22a5 - solute carrier family 22 (organic cation transporter), member 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: jvs; Lstpl; Octn2

基因 ID: 20520 | 基因类型: protein coding

关于 Slc22a5

功能概要

Enables (R)-carnitine transmembrane transporter activity. Involved in (R)-carnitine transmembrane transport and transport across blood-brain barrier. Acts upstream of or within several processes, including adult heart development; carnitine metabolic process; and carnitine transport. Located in brush border membrane. Is expressed in several structures, including liver; metanephros; nasal cavity mucosa; spleen; and testis. Used to study systemic primary carnitine deficiency disease. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a5 基因产物(3)

mRNA Protein Name
NM_001362711.1 NP_001349640.1 solute carrier family 22 member 5 isoform 2
NM_001362712.1 NP_001349641.1 solute carrier family 22 member 5 isoform 2
NM_011396.3 NP_035526.1 solute carrier family 22 member 5 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables (R)-carnitine transmembrane transporter activity IDA
IDA: 通过直接分析推断
20722056 MGI
enables (R)-carnitine transmembrane transporter activity IMP
IMP: 通过突变表型推断
14595704 MGI
enables carnitine transmembrane transporter activity IDA
IDA: 通过直接分析推断
10454528 MGI
enables carnitine transmembrane transporter activity IMP
IMP: 通过突变表型推断
9634010 MGI
enables quaternary ammonium group transmembrane transporter activity IDA
IDA: 通过直接分析推断
11010964 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in (R)-carnitine transmembrane transport IDA
IDA: 通过直接分析推断
10454528 MGI
involved in (R)-carnitine transmembrane transport IMP
IMP: 通过突变表型推断
14595704 MGI
involved in (R)-carnitine transport IDA
IDA: 通过直接分析推断
20722056 MGI
acts upstream of or within adult heart development IMP
IMP: 通过突变表型推断
9140816 MGI
acts upstream of or within carnitine metabolic process IMP
IMP: 通过突变表型推断
1996978 MGI
acts upstream of or within carnitine transport IDA
IDA: 通过直接分析推断
11010964 MGI
acts upstream of or within carnitine transport IMP
IMP: 通过突变表型推断
8155735 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
8670273 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
17027329 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
7773507 MGI
acts upstream of or within quaternary ammonium group transport IDA
IDA: 通过直接分析推断
11010964 MGI
acts upstream of or within reproductive structure development IMP
IMP: 通过突变表型推断
10100867 MGI
involved in response to tumor necrosis factor IDA
IDA: 通过直接分析推断
20722056 MGI
involved in response to type II interferon IDA
IDA: 通过直接分析推断
20722056 MGI
involved in transport across blood-brain barrier IMP
IMP: 通过突变表型推断
14595704 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
20722056 MGI
located in brush border membrane IDA
IDA: 通过直接分析推断
15523054 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

solute carrier family 22 member 5

high-affinity sodium-dependent carnitine cotransporter

juvenile visceral steatosis

organic cation/carnitine transporter 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13077 SLC22A5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20645 Slc22a5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27155 Slc22a5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc22a5 NCBI NCBI:6584
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