2. Gene
  3. Slc6a2 - solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Gene

Slc6a2 - solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NET; NE-T; Slc6a5

基因 ID: 20538 | 基因类型: protein coding

关于 Slc6a2

功能概要

Enables monoamine transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in neurotransmitter reuptake and norepinephrine uptake. Acts upstream of or within neurotransmitter transport and response to pain. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection; neuronal cell body membrane; and presynaptic membrane. Predicted to be integral component of plasma membrane. Is expressed in adrenal gland; lip; nervous system; sensory organ; and testis. Used to study heart conduction disease. Human ortholog(s) of this gene implicated in hypertension and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a2 基因产物(1)

mRNA Protein Name
NM_009209.3 NP_033235.3 sodium-dependent noradrenaline transporter
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monoamine transmembrane transporter activity IMP
IMP: 通过突变表型推断
20858707 MGI
enables neurotransmitter transmembrane transporter activity IMP
IMP: 通过突变表型推断
20858707 MGI
enables norepinephrine:sodium symporter activity IDA
IDA: 通过直接分析推断
16269905 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neurotransmitter reuptake IDA
IDA: 通过直接分析推断
10769386 MGI
involved in neurotransmitter reuptake IMP
IMP: 通过突变表型推断
10769386 MGI
acts upstream of or within neurotransmitter transport IDA
IDA: 通过直接分析推断
11805341 MGI
involved in neurotransmitter transport IMP
IMP: 通过突变表型推断
20858707 MGI
involved in norepinephrine uptake IMP
IMP: 通过突变表型推断
20858707 MGI
acts upstream of or within response to pain IMP
IMP: 通过突变表型推断
11805341 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sodium-dependent noradrenaline transporter

NE transporter

norepinephrine transporter

solute carrier family 6 member 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13306 SLC6A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20194 Slc6a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26699 Slc6a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc6a2 NCBI NCBI:6530
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