2. Gene
  3. Slc9a1 - solute carrier family 9 (sodium/hydrogen exchanger), member 1 Gene

Slc9a1 - solute carrier family 9 (sodium/hydrogen exchanger), member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: swe; Apnh; Nhe1; Mir5122; mir-5122

基因 ID: 20544 | 基因类型: protein coding

关于 Slc9a1

功能概要

Enables sodium:proton antiporter activity. Acts upstream of or within several processes, including regulation of pH; response to acidic pH; and sodium ion transport. Located in apical plasma membrane. Is expressed in several structures, including alimentary system; early conceptus; nervous system; oocyte; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 19 and congestive heart failure. Orthologous to human SLC9A1 (solute carrier family 9 member A1). [provided by Alliance of Genome Resources, Apr 2022]

Slc9a1 基因产物(2)

mRNA Protein Name
NM_001358455.1 NP_001345384.1 sodium/hydrogen exchanger 1 isoform 2
NM_016981.3 NP_058677.1 sodium/hydrogen exchanger 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
10666043 MGI
enables sodium:proton antiporter activity IMP
IMP: 通过突变表型推断
23677982 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac muscle cell differentiation IMP
IMP: 通过突变表型推断
19011045 MGI
acts upstream of or within embryo development IMP
IMP: 通过突变表型推断
23677982 MGI
acts upstream of or within regulation of pH IDA
IDA: 通过直接分析推断
10666043 MGI
acts upstream of or within regulation of pH IMP
IMP: 通过突变表型推断
10673550 MGI
acts upstream of or within response to acidic pH IMP
IMP: 通过突变表型推断
10673550 MGI
acts upstream of or within sodium ion transport IDA
IDA: 通过直接分析推断
10666043 MGI
acts upstream of or within stem cell differentiation IMP
IMP: 通过突变表型推断
19011045 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
21705333 MGI
located in membrane IDA
IDA: 通过直接分析推断
12619893 MGI
part of transporter complex IDA
IDA: 通过直接分析推断
23904602 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sodium/hydrogen exchanger 1

NHE-1

Na(+)/H(+) exchanger 1

Na+/H+ antiporter

Na+/H+, amiloride sensitive

slow-wave epilepsy

solute carrier family 9, member 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13341 SLC9A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13349 SLC9B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19075 Slc9a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25566 Slc9a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc9a1 NCBI NCBI:6548
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