2. Gene
  3. Kdm5c - lysine (K)-specific demethylase 5C Gene

Kdm5c - lysine (K)-specific demethylase 5C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Smcx; Jarid1c; mKIAA0234; D930009K15Rik

基因 ID: 20591 | 基因类型: protein coding

关于 Kdm5c

功能概要

Predicted to enable several functions, including histone H3-tri/di/monomethyl-lysine-4 demethylase activity; identical protein binding activity; and zinc ion binding activity. Involved in negative regulation of transcription, DNA-templated. Acts upstream of or within histone H3-K4 demethylation. Located in nucleus. Is expressed in several structures, including brain; early conceptus; gonad; limb; and metanephros. Used to study syndromic X-linked intellectual disability Claes-Jensen type. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Claes-Jensen type. Orthologous to human KDM5C (lysine demethylase 5C). [provided by Alliance of Genome Resources, Apr 2022]

Kdm5c 基因产物(7)

mRNA Protein Name
NM_001403071.1 NP_001390000.1 lysine-specific demethylase 5C isoform 2
NM_001403072.1 NP_001390001.1 lysine-specific demethylase 5C isoform 3
NM_001403073.1 NP_001390002.1 lysine-specific demethylase 5C isoform 4
NM_001403074.1 NP_001390003.1 lysine-specific demethylase 5C isoform 5
NM_001403075.1 NP_001390004.1 lysine-specific demethylase 5C isoform 6
NM_001403076.1 NP_001390005.1 lysine-specific demethylase 5C isoform 7
NM_013668.5 NP_038696.2 lysine-specific demethylase 5C isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K4 demethylase activity IDA
IDA: 通过直接分析推断
23246292 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
21960634 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
23246292 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 5C

[histone H3]-trimethyl-L-lysine(4) demethylase 5C

histone demethylase JARID1C

jumonji, AT rich interactive domain 1C (Rbp2 like)

jumonji/ARID domain-containing protein 1C

selected mouse cDNA on the X

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120400 KDM5-C70 Inhibitor 98.82% 否
HY-102047B KDOAM-25 citrate Inhibitor 98.56% 否
HY-100014 KDM5A-IN-1 Inhibitor 99.64% 否
HY-119397A KDM5-C49 hydrochloride Inhibitor 98.22% 否
HY-100764 YUKA1 Inhibitor 99.15% 否
HY-102047 KDOAM-25 Inhibitor / 否
HY-RS07220 KDM5C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-102047A KDOAM-25 trihydrochloride Inhibitor / 否
HY-119397 KDM5-C49 Inhibitor / 否
HY-RS16858 Kdm5c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23299 Kdm5c Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm5c NCBI NCBI:8242
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