2. Gene
  3. Sox11 - SRY (sex determining region Y)-box 11 Gene

Sox11 - SRY (sex determining region Y)-box 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: end1; 1110038H03Rik; 6230403H02Rik

基因 ID: 20666 | 基因类型: protein coding

关于 Sox11

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; nervous system development; and regulation of gene expression. Acts upstream of or within skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 9. Orthologous to human SOX11 (SRY-box transcription factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Sox11 基因产物(1)

mRNA Protein Name
NM_009234.6 NP_033260.4 transcription factor SOX-11
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
18403418 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
18505825 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
21527504 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
19808959 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
18505825 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in closure of optic fissure IMP
IMP: 通过突变表型推断
18423449 MGI
involved in cornea development in camera-type eye IMP
IMP: 通过突变表型推断
18423449 MGI
involved in embryonic digestive tract morphogenesis IMP
IMP: 通过突变表型推断
15254231 MGI
involved in embryonic skeletal system morphogenesis IMP
IMP: 通过突变表型推断
15254231 MGI
involved in eyelid development in camera-type eye IMP
IMP: 通过突变表型推断
15254231 MGI
involved in glial cell development IMP
IMP: 通过突变表型推断
20147379 MGI
involved in glial cell proliferation IMP
IMP: 通过突变表型推断
20147379 MGI
involved in hard palate development IMP
IMP: 通过突变表型推断
15254231 MGI
involved in lens morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
18423449 MGI
involved in lung morphogenesis IMP
IMP: 通过突变表型推断
15254231 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
19808959 MGI
involved in negative regulation of glial cell proliferation IMP
IMP: 通过突变表型推断
19808959 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19808959 MGI
involved in nervous system development IMP
IMP: 通过突变表型推断
20596238 MGI
involved in neuroepithelial cell differentiation IMP
IMP: 通过突变表型推断
20646169 MGI
involved in noradrenergic neuron differentiation IMP
IMP: 通过突变表型推断
20147379 MGI
involved in outflow tract morphogenesis IMP
IMP: 通过突变表型推断
15254231 MGI
involved in positive regulation of BMP signaling pathway IMP
IMP: 通过突变表型推断
18423449 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
21527504 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
18423449 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
19808959 MGI
involved in positive regulation of hippo signaling IMP
IMP: 通过突变表型推断
20596238 MGI
involved in positive regulation of hormone secretion IMP
IMP: 通过突变表型推断
21527504 MGI
involved in positive regulation of lens epithelial cell proliferation IMP
IMP: 通过突变表型推断
18423449 MGI
involved in positive regulation of neurogenesis IDA
IDA: 通过直接分析推断
19490090 MGI
involved in positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
19490090 MGI
involved in positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
19808959 MGI
involved in positive regulation of ossification IMP
IMP: 通过突变表型推断
15254231 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18403418 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
20847309 MGI
involved in soft palate development IMP
IMP: 通过突变表型推断
15254231 MGI
involved in spinal cord development IMP
IMP: 通过突变表型推断
20646169 MGI
involved in sympathetic nervous system development IMP
IMP: 通过突变表型推断
20147379 MGI
involved in ventricular septum morphogenesis IMP
IMP: 通过突变表型推断
15254231 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15456859 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor SOX-11

SRY-box containing gene 11

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13584 SOX11 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21764 Sox11 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28281 Sox11 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sox11 NCBI NCBI:6664
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