2. Gene
  3. Sox3 - SRY (sex determining region Y)-box 3 Gene

Sox3 - SRY (sex determining region Y)-box 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sox-3

基因 ID: 20675 | 基因类型: protein coding

关于 Sox3

功能概要

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including diencephalon development; face development; and sex determination. Acts upstream of or within animal organ development and spermatid differentiation. Predicted to be located in nucleoplasm. Is expressed in several structures, including brain; branchial arch; early conceptus; embryo ectoderm; and gonad. Used to study hydrocephalus. Human ortholog(s) of this gene implicated in X-linked panhypopituitarism. Orthologous to human SOX3 (SRY-box transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Sox3 基因产物(1)

mRNA Protein Name
NM_009237.3 NP_033263.2 transcription factor SOX-3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
8625802 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11875113 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Sertoli cell development IEP
IEP: 通过表达模式推断
11875113 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
14981518 MGI
involved in face development IMP
IMP: 通过突变表型推断
17728342 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
14981518 MGI
involved in hypothalamus development IMP
IMP: 通过突变表型推断
14981518 MGI
involved in pituitary gland development IMP
IMP: 通过突变表型推断
14981518 MGI
involved in sensory organ development IMP
IMP: 通过突变表型推断
17728342 MGI
involved in sex determination IMP
IMP: 通过突变表型推断
21183788 MGI
acts upstream of or within spermatid differentiation IMP
IMP: 通过突变表型推断
15893302 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor SOX-3

SRY-box containing gene 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13593 SOX3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22330 Sox3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28852 Sox3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sox3 NCBI NCBI:6658
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