2. Gene
  3. Aph1b - aph1 homolog B, gamma secretase subunit Gene

Aph1b - aph1 homolog B, gamma secretase subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: APH-1b; aph-1beta

基因 ID: 208117 | 基因类型: protein coding

关于 Aph1b

功能概要

Predicted to enable endopeptidase activator activity and protein-macromolecule adaptor activity. Acts upstream of or within several processes, including amyloid-beta formation; chemical synaptic transmission; and prepulse inhibition. Part of gamma-secretase complex. Is expressed in several structures, including nervous system. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human APH1B (aph-1 homolog B, gamma-secretase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Aph1b 基因产物(1)

mRNA Protein Name
NM_177583.4 NP_808251.1 gamma-secretase subunit APH-1B
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within amyloid-beta formation IGI
IGI: 通过遗传相互作用推断
16371134 MGI
acts upstream of or within membrane protein ectodomain proteolysis IGI
IGI: 通过遗传相互作用推断
18626010 MGI
acts upstream of or within prepulse inhibition IGI
IGI: 通过遗传相互作用推断
18626010 MGI
acts upstream of or within short-term memory IGI
IGI: 通过遗传相互作用推断
18626010 MGI
acts upstream of or within synaptic transmission, dopaminergic IGI
IGI: 通过遗传相互作用推断
18626010 MGI
acts upstream of or within synaptic transmission, glutamatergic IGI
IGI: 通过遗传相互作用推断
18626010 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of gamma-secretase complex IDA
IDA: 通过直接分析推断
16371134 MGI
part of gamma-secretase complex IGI
IGI: 通过遗传相互作用推断
18626010 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gamma-secretase subunit APH-1B

APH1B homolog

anterior pharynx defective 1b homolog

anterior pharynx defective 1c homolog

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-156011 PSEN1-IN-1 Inhibitor / 否
HY-156012 PSEN1-IN-2 Inhibitor / 否
HY-RS00818 APH1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22392 Aph1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28916 Aph1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aph1b NCBI NCBI:83464
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z