2. Gene
  3. Syt1 - synaptotagmin I Gene

Syt1 - synaptotagmin I Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SytI; G630098F17Rik

基因 ID: 20979 | 基因类型: protein coding

关于 Syt1

功能概要

Enables several functions, including calcium ion sensor activity; calcium-dependent phospholipid binding activity; and syntaxin-1 binding activity. Involved in modulation of chemical synaptic transmission; regulation of dopamine secretion; and synaptic vesicle exocytosis. Acts upstream of or within calcium ion-regulated exocytosis of neurotransmitter; spontaneous neurotransmitter secretion; and synchronous neurotransmitter secretion. Located in several cellular components, including glutamatergic synapse; presynaptic membrane; and secretory vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Orthologous to human SYT1 (synaptotagmin 1). [provided by Alliance of Genome Resources, Apr 2022]

Syt1 基因产物(8)

mRNA Protein Name
NM_001252341.1 NP_001239270.1 synaptotagmin-1 isoform 1
NM_001252342.1 NP_001239271.1 synaptotagmin-1 isoform 2
NM_001358501.1 NP_001345430.1 synaptotagmin-1 isoform 2
NM_001358502.1 NP_001345431.1 synaptotagmin-1 isoform 1
NM_001358503.1 NP_001345432.1 synaptotagmin-1 isoform 1
NM_001358504.1 NP_001345433.1 synaptotagmin-1 isoform 2
NM_001358506.1 NP_001345435.1 synaptotagmin-1 isoform 2
NM_009306.3 NP_033332.1 synaptotagmin-1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
15197251 MGI
enables calcium ion sensor activity IDA
IDA: 通过直接分析推断
21521611 MGI
enables calcium-dependent phospholipid binding IDA
IDA: 通过直接分析推断
8626542 MGI
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
15774481 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14726597 MGI
enables syntaxin-1 binding IDA
IDA: 通过直接分析推断
18703708 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium ion-regulated exocytosis of neurotransmitter IMP
IMP: 通过突变表型推断
21521611 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IDA
IDA: 通过直接分析推断
7954835 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IEP
IEP: 通过表达模式推断
7954835 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IMP
IMP: 通过突变表型推断
7954835 MGI
involved in fast, calcium ion-dependent exocytosis of neurotransmitter IDA
IDA: 通过直接分析推断
12526776 MGI
involved in fast, calcium ion-dependent exocytosis of neurotransmitter IMP
IMP: 通过突变表型推断
7954835 MGI
acts upstream of or within neurotransmitter secretion IDA
IDA: 通过直接分析推断
15197251 MGI
involved in positive regulation of calcium ion-dependent exocytosis of neurotransmitter IMP
IMP: 通过突变表型推断
11242035 MGI
involved in positive regulation of synaptic transmission IMP
IMP: 通过突变表型推断
7954835 MGI
involved in regulation of calcium ion-dependent exocytosis IMP
IMP: 通过突变表型推断
11562488 MGI
involved in regulation of dopamine secretion IMP
IMP: 通过突变表型推断
21576241 MGI
involved in regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
12526776 MGI
acts upstream of or within spontaneous neurotransmitter secretion IMP
IMP: 通过突变表型推断
21521611 MGI
acts upstream of or within synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
21040848 MGI
acts upstream of or within synchronous neurotransmitter secretion IMP
IMP: 通过突变表型推断
21521611 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
14622145 MGI
located in axon IDA
IDA: 通过直接分析推断
21576241 MGI
located in dense core granule IDA
IDA: 通过直接分析推断
18468511 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
7954835 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
7954835 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
7954835 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
14622145 MGI
located in presynaptic membrane IDA
IDA: 通过直接分析推断
15197251 MGI
located in secretory granule IDA
IDA: 通过直接分析推断
12145198 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
16407767 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
15071120 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

synaptotagmin-1

p65

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P5043 α-Synuclein (67-78) (human) / 否
HY-RS14106 SYT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22338 Syt1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28860 Syt1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syt1 NCBI NCBI:6857
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