2. Gene
  3. Fancd2 - Fanconi anemia, complementation group D2 Gene

Fancd2 - Fanconi anemia, complementation group D2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FA4; FAD; FACD; FA-D2; FANCD; 2410150O07Rik

基因 ID: 211651 | 基因类型: protein coding

关于 Fancd2

功能概要

Predicted to enable DNA Polymerase binding activity. Acts upstream of or within several processes, including homologous chromosome pairing at meiosis; neuronal stem cell population maintenance; and regulation of regulatory T cell differentiation. Located in condensed chromosome and nucleus. Used to study Fanconi anemia complementation group D2. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group D2; and breast Cancer. Orthologous to human FANCD2 (FA complementation group D2). [provided by Alliance of Genome Resources, Apr 2022]

Fancd2 基因产物(2)

mRNA Protein Name
NM_001033244.3 NP_001028416.2 Fanconi anemia group D2 protein homolog isoform 1
NM_001347350.1 NP_001334279.1 Fanconi anemia group D2 protein homolog isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17304220 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA damage response IMP
IMP: 通过突变表型推断
12893777 MGI
acts upstream of or within brain morphogenesis IGI
IGI: 通过遗传相互作用推断
24483844 MGI
acts upstream of or within cellular response to oxidative stress IGI
IGI: 通过遗传相互作用推断
24483844 MGI
acts upstream of or within gamete generation IMP
IMP: 通过突变表型推断
12893777 MGI
acts upstream of or within homologous chromosome pairing at meiosis IMP
IMP: 通过突变表型推断
12893777 MGI
acts upstream of or within neuronal stem cell population maintenance IGI
IGI: 通过遗传相互作用推断
24483844 MGI
acts upstream of or within regulation of CD40 signaling pathway IMP
IMP: 通过突变表型推断
24501220 MGI
acts upstream of or within regulation of DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
24501220 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: 通过突变表型推断
24501220 MGI
acts upstream of or within regulation of regulatory T cell differentiation IMP
IMP: 通过突变表型推断
24501220 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in condensed chromosome IDA
IDA: 通过直接分析推断
12913077 MGI
located in nucleus IDA
IDA: 通过直接分析推断
24001775 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Fanconi anemia group D2 protein homolog

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-160700 TNG348 Inhibitor 99.74% Phase 2
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14520 Tetrahydrofolic acid 96.77% 否
HY-123834 FEN1-IN-1 99.85% 否
HY-153365 I-138 Inhibitor 99.75% 否
HY-126539 UBE2T/FANCL-IN-1 99.83% 否
HY-14520A (6S)-Tetrahydrofolic acid / 否
HY-RS04735 FANCD2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-14520B Tetrahydrofolic acid trihydrochloride / 否
HY-RS17257 Fancd2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23711 Fancd2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fancd2 NCBI NCBI:2177
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