2. Gene
  3. Arid5a - AT rich interactive domain 5A (MRF1-like) Gene

Arid5a - AT rich interactive domain 5A (MRF1-like) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mrf1; D430024K22Rik

基因 ID: 214855 | 基因类型: protein coding

关于 Arid5a

功能概要

Enables RNA stem-loop binding activity and chromatin binding activity. Involved in cellular response to lipopolysaccharide; positive regulation of T-helper 17 type immune response; and positive regulation of cytokine production. Acts upstream of or within chondrocyte differentiation; positive regulation of histone acetylation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including ear; heart; hemolymphoid system; nervous system; and neural retina. Orthologous to human ARID5A (AT-rich interaction domain 5A). [provided by Alliance of Genome Resources, Apr 2022]

Arid5a 基因产物(5)

mRNA Protein Name
NM_001172205.1 NP_001165676.1 AT-rich interactive domain-containing protein 5A isoform 1
NM_001172206.1 NP_001165677.1 AT-rich interactive domain-containing protein 5A isoform 2
NM_001290726.1 NP_001277655.1 AT-rich interactive domain-containing protein 5A isoform 5
NM_001290727.1 NP_001277656.1 AT-rich interactive domain-containing protein 5A isoform 6
NM_145996.4 NP_666108.2 AT-rich interactive domain-containing protein 5A isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA stem-loop binding IDA
IDA: 通过直接分析推断
27671645 MGI
enables RNA stem-loop binding IMP
IMP: 通过突变表型推断
27022145 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
21346191 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21346191 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
21346191 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
27671645 MGI
acts upstream of or within chondrocyte differentiation IDA
IDA: 通过直接分析推断
21346191 MGI
involved in positive regulation of T-helper 1 cell cytokine production IMP
IMP: 通过突变表型推断
27671645 MGI
involved in positive regulation of T-helper 17 type immune response IMP
IMP: 通过突变表型推断
27022145 MGI
involved in positive regulation of interleukin-17 production IMP
IMP: 通过突变表型推断
27022145 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
27671645 MGI
acts upstream of or within positive regulation of protein acetylation IDA
IDA: 通过直接分析推断
21346191 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
21346191 MGI
involved in positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
27671645 MGI
involved in positive regulation of type II interferon production IMP
IMP: 通过突变表型推断
27022145 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
21346191 MGI
part of transcription regulator complex IPI
IPI: 通过物理相互作用推断
21346191 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

AT-rich interactive domain-containing protein 5A

ARID domain-containing protein 5A

AT rich interactive domain 5A (Mrf1 like)

modulator recognition factor I

Arid5a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Arid5a Q3U108 SOX9 Homo sapiens P48436
Confocal
21346191
种属间
Arid5a Q3U108 SOX9 Homo sapiens P48436
Anti Tag CoIP
21346191
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N10295 Flavipin Agonist / 否
HY-RS00973 ARID5A Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arid5a NCBI NCBI:10865
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