2. Gene
  3. Tdg - thymine DNA glycosylase Gene

Tdg - thymine DNA glycosylase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Jza1; JZA-3; E130317C12Rik

基因 ID: 21665 | 基因类型: protein coding

关于 Tdg

功能概要

Enables several functions, including SUMO binding activity; protein kinase C binding activity; and transcription coregulator activity. Involved in DNA metabolic process; regulation of embryonic development; and regulation of gene expression, epigenetic. Acts upstream of or within negative regulation of chromatin binding activity; negative regulation of protein binding activity; and negative regulation of transcription by RNA polymerase II. Located in PML body. Is expressed in several structures, including epithelium; genitourinary system; nervous system; retina; and skin. Orthologous to human TDG (thymine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Tdg 基因产物(3)

mRNA Protein Name
NM_001358517.1 NP_001345446.1 G/T mismatch-specific thymine DNA glycosylase isoform 3
NM_011561.3 NP_035691.2 G/T mismatch-specific thymine DNA glycosylase isoform 1
NM_172552.4 NP_766140.2 G/T mismatch-specific thymine DNA glycosylase isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA N-glycosylase activity IDA
IDA: 通过直接分析推断
21722948 MGI
enables DNA binding IDA
IDA: 通过直接分析推断
21817016 MGI
enables SUMO binding IPI
IPI: 通过物理相互作用推断
15569683 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16282588 MGI
enables protein kinase C binding IPI
IPI: 通过物理相互作用推断
19966277 MGI
enables transcription coregulator activity IGI
IGI: 通过遗传相互作用推断
18945672 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in base-excision repair IDA
IDA: 通过直接分析推断
21817016 MGI
involved in epigenetic regulation of gene expression IMP
IMP: 通过突变表型推断
21278727 MGI
acts upstream of or within negative regulation of chromatin binding IDA
IDA: 通过直接分析推断
18945672 MGI
acts upstream of or within negative regulation of protein binding IDA
IDA: 通过直接分析推断
18945672 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
18945672 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18945672 MGI
involved in regulation of embryonic development IMP
IMP: 通过突变表型推断
21278727 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in PML body IDA
IDA: 通过直接分析推断
15569683 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15569683 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

G/T mismatch-specific thymine DNA glycosylase

C-JUN leucine zipper interactive protein JZA-3

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-130208 Thiodigalactoside Inhibitor 99.97% 否
HY-126181 5-Formylcytosine 96.4% 否
HY-RS14329 TDG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17123 Tdg Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23568 Tdg Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tdg NCBI NCBI:6996
Rattus norvegicus Tdg NCBI NCBI:114521
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