2. Gene
  3. Tead1 - TEA domain family member 1 Gene

Tead1 - TEA domain family member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TEF-1; Tcf13; TEAD-1; mTEF-1; Gtrgeo5; 2610024B07Rik; B230114H05Rik

基因 ID: 21676 | 基因类型: protein coding

关于 Tead1

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; cellular response to retinoic acid; and hippo signaling. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; musculature; and tooth. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to human TEAD1 (TEA domain transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tead1 基因产物(3)

mRNA Protein Name
NM_001166584.2 NP_001160056.2 transcriptional enhancer factor TEF-1 isoform 1
NM_001166585.2 NP_001160057.2 transcriptional enhancer factor TEF-1 isoform 3
NM_009346.4 NP_033372.2 transcriptional enhancer factor TEF-1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
14762206 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11306707 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14762206 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to retinoic acid IDA
IDA: 通过直接分析推断
21385842 MGI
acts upstream of or within embryonic heart tube morphogenesis IGI
IGI: 通过遗传相互作用推断
18332127 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
7958896 MGI
acts upstream of or within hippo signaling IGI
IGI: 通过遗传相互作用推断
19004856 MGI
acts upstream of or within lateral mesoderm development IGI
IGI: 通过遗传相互作用推断
18332127 MGI
acts upstream of or within notochord development IGI
IGI: 通过遗传相互作用推断
18332127 MGI
acts upstream of or within paraxial mesoderm development IGI
IGI: 通过遗传相互作用推断
18332127 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
26902285 MGI
acts upstream of or within positive regulation of protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
18978355 MGI
acts upstream of or within positive regulation of stem cell population maintenance IGI
IGI: 通过遗传相互作用推断
20516196 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11358867 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16207754 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17689488 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
14762206 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
19004856 MGI
acts upstream of or within regulation of gene expression IGI
IGI: 通过遗传相互作用推断
27288457 MGI
acts upstream of or within transition between fast and slow fiber IDA
IDA: 通过直接分析推断
18978355 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of TEAD-YAP complex IPI
IPI: 通过物理相互作用推断
11358867 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19004856 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
16207754 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcriptional enhancer factor TEF-1

NTEF-1

TCF-13

transcription factor 13

相关产品

Pre-clinical Phase
生物活性分子 (21)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-134956 VT104 Inhibitor 99.94% 否
HY-134955 VT103 Inhibitor 99.64% 否
HY-147135 MYF-03-69 98.11% 否
HY-P2244A YAP-TEAD-IN-1 TFA Inhibitor 99.99% 否
HY-147208 MSC-4106 Inhibitor 99.87% 否
HY-147136 MYF-03-176 Inhibitor 99.72% 否
HY-P2244 YAP-TEAD-IN-1 Inhibitor 99.69% 否
HY-147088 TEAD-IN-2 Inhibitor 98.14% 否
HY-172113 H122 98.04% 否
HY-174275 TEAD1/3/4-IN-1 Inhibitor 99.04% 否
HY-161569 TEAD-IN-11 Inhibitor 99.82% 否
HY-161443 TEAD-IN-9 Inhibitor / 否
HY-161568 TEAD-IN-10 Inhibitor / 否
HY-168506 MSC-1254 Inhibitor / 否
HY-169316 YAP/TAZ inhibitor-4 Inhibitor / 否
HY-170764 M3686 Inhibitor / 否
HY-173139 TEAD-IN-19 Inhibitor / 否
HY-RS14342 TEAD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-168505 MSC-5046 Inhibitor / 否
HY-RS17084 Tead1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23528 Tead1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tead1 NCBI NCBI:7003
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