2. Gene
  3. Trib2 - tribbles pseudokinase 2 Gene

Trib2 - tribbles pseudokinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TRB2; TRB-2

基因 ID: 217410 | 基因类型: protein coding

关于 Trib2

功能概要

Enables ubiquitin protein Ligase binding activity and ubiquitin-protein transferase regulator activity. Involved in negative regulation of fat cell differentiation and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and Cytoskeleton. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and integumental system. Orthologous to human TRIB2 (tribbles pseudokinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Trib2 基因产物(1)

mRNA Protein Name
NM_144551.6 NP_653134.2 tribbles homolog 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II-specific DNA-binding transcription factor binding IDA
IDA: 通过直接分析推断
17576771 MGI
enables ubiquitin protein ligase binding IDA
IDA: 通过直接分析推断
20410507 MGI
enables ubiquitin-protein transferase regulator activity IDA
IDA: 通过直接分析推断
20410507 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
17576771 MGI
involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
20410507 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tribbles homolog 2

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168274 PROTAC TRIB2 degrader-1 Inducer / 否
HY-168276 Boc-Nonanol / 否
HY-168277 5-Aminothalidomide-C9-Boc / 否
HY-RS15016 TRIB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-168275 TRIB2 ligand-1 / 否
HY-RS19489 Trib2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25983 Trib2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trib2 NCBI NCBI:28951
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