1. Gene
  2. Flvcr2 - feline leukemia virus subgroup C cellular receptor 2 Gene

Flvcr2 - feline leukemia virus subgroup C cellular receptor 2 Gene

种属: Mus musculus

同用名: CCT; Mfsd7c

基因 ID: 217721 | 基因类型: protein coding

关于 Flvcr2

功能概要

Predicted to enable heme binding activity and heme transmembrane transporter activity. Predicted to be involved in heme export. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system and yolk sac. Used to study proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Human ortholog(s) of this gene implicated in proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Orthologous to human FLVCR2 (FLVCR heme transporter 2). [provided by Alliance of Genome Resources, Apr 2022]

Flvcr2 基因产物(1)

mRNA Protein Name
NM_145447.2 NP_663422.1 feline leukemia virus subgroup C receptor-related protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables choline binding IDA
IDA: 通过直接分析推断
38693257 MGI
enables choline transmembrane transporter activity IDA
IDA: 通过直接分析推断
38302740 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
32973183 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
32369453 MGI
involved in choline transport IDA
IDA: 通过直接分析推断
38693257 MGI
acts upstream of or within choline transport IMP
IMP: 通过突变表型推断
38693257 MGI
acts upstream of or within endothelial tip cell fate specification IMP
IMP: 通过突变表型推断
32369453 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
32369453 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
32369453 MGI
acts upstream of or within sprouting angiogenesis IMP
IMP: 通过突变表型推断
32369453 MGI
involved in transport across blood-brain barrier IDA
IDA: 通过直接分析推断
38302740 MGI
acts upstream of or within transport across blood-brain barrier IMP
IMP: 通过突变表型推断
38693257 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in plasma membrane IDA
IDA: 通过直接分析推断
38302740 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

feline leukemia virus subgroup C receptor-related protein 2

calcium-chelate transporter

feline leukemia virus subgroup C cellular receptor family, member 2

major facilitator superfamily domain containing 7C

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Flvcr2 NCBI NCBI:55640