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  3. Tnnt2 - troponin T2, cardiac Gene

Tnnt2 - troponin T2, cardiac Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tnt; cTnT

基因 ID: 21956 | 基因类型: protein coding

关于 Tnnt2

功能概要

A structural constituent of Cytoskeleton. Acts upstream of or within several processes, including cardiac muscle tissue morphogenesis; response to bacterium; and sarcomere organization. Located in sarcomere. Part of troponin complex. Is expressed in several structures, including crus of diaphragm; embryo mesenchyme; heart; musculature; and urogenital sinus. Used to study dilated cardiomyopathy 1D and hypertrophic cardiomyopathy 2. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type). [provided by Alliance of Genome Resources, Apr 2022]

Tnnt2 基因产物(9)

mRNA Protein Name
NM_001130174.2 NP_001123646.1 troponin T, cardiac muscle isoform a
NM_001130175.2 NP_001123647.4 troponin T, cardiac muscle isoform g
NM_001130176.1 NP_001123648.1 troponin T, cardiac muscle isoform b
NM_001130177.2 NP_001123649.1 troponin T, cardiac muscle isoform c
NM_001130178.2 NP_001123650.1 troponin T, cardiac muscle isoform d
NM_001130179.2 NP_001123651.4 troponin T, cardiac muscle isoform h
NM_001130180.2 NP_001123652.1 troponin T, cardiac muscle isoform e
NM_001130181.2 NP_001123653.4 troponin T, cardiac muscle isoform i
NM_011619.3 NP_035749.1 troponin T, cardiac muscle isoform f
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables structural constituent of cytoskeleton IDA
IDA: 通过直接分析推断
12832403 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within atrial cardiac muscle tissue morphogenesis IMP
IMP: 通过突变表型推断
10449439 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
9637714 MGI
acts upstream of or within muscle contraction IDA
IDA: 通过直接分析推断
12832403 MGI
acts upstream of or within regulation of heart contraction IMP
IMP: 通过突变表型推断
11158969 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
acts upstream of or within sarcomere organization IMP
IMP: 通过突变表型推断
10449439 MGI
acts upstream of or within ventricular cardiac muscle tissue morphogenesis IMP
IMP: 通过突变表型推断
16326803 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in myofibril IDA
IDA: 通过直接分析推断
10449439 MGI
located in sarcomere IDA
IDA: 通过直接分析推断
12738802 MGI
located in sarcoplasm IDA
IDA: 通过直接分析推断
15830381 MGI
part of troponin complex IDA
IDA: 通过直接分析推断
12832403 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

troponin T, cardiac muscle

cardiac TnT

cardiac muscle troponin T

tnTc

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14855 TNNT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22869 Tnnt2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29383 Tnnt2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnnt2 NCBI NCBI:7139
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