1. Gene
  2. Vamp8 - vesicle-associated membrane protein 8 Gene

Vamp8 - vesicle-associated membrane protein 8 Gene

种属: Mus musculus

同用名: Edb; endobrevin

基因 ID: 22320 | 基因类型: protein coding

关于 Vamp8

功能概要

Predicted to enable SNAP receptor activity; Chloride Channel Inhibitor activity; and syntaxin binding activity. Involved in SNARE complex assembly and mucus secretion. Acts upstream of or within several processes, including cellular response to interferon-gamma; positive regulation of pancreatic amylase secretion; and zymogen granule exocytosis. Located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and lysosome. Part of SNARE complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human VAMP8 (vesicle associated membrane protein 8). [provided by Alliance of Genome Resources, Apr 2022]

Vamp8 基因产物(1)

mRNA Protein Name
NM_016794.3 NP_058074.2 vesicle-associated membrane protein 8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14668490 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SNARE complex assembly IDA
IDA: 通过直接分析推断
21151919 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: 通过直接分析推断
19144319 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
18535671 MGI
involved in mucus secretion IMP
IMP: 通过突变表型推断
22144578 MGI
acts upstream of or within positive regulation of pancreatic amylase secretion IMP
IMP: 通过突变表型推断
18535671 MGI
acts upstream of or within regulation of endocytosis IMP
IMP: 通过突变表型推断
18227281 MGI
acts upstream of or within vesicle fusion IMP
IMP: 通过突变表型推断
18535671 MGI
acts upstream of or within zymogen granule exocytosis IMP
IMP: 通过突变表型推断
18535671 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SNARE complex IDA
IDA: 通过直接分析推断
18535671 MGI
located in basal part of cell IDA
IDA: 通过直接分析推断
18535671 MGI
located in basolateral part of cell IDA
IDA: 通过直接分析推断
18535671 MGI
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
18535671 MGI
located in cell surface IDA
IDA: 通过直接分析推断
21151919 MGI
located in cytosol IDA
IDA: 通过直接分析推断
22589474 MGI
located in lysosome IDA
IDA: 通过直接分析推断
27628032 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
19144319 MGI
located in secretory granule IDA
IDA: 通过直接分析推断
18321981 MGI
located in zymogen granule IDA
IDA: 通过直接分析推断
18535671 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

vesicle-associated membrane protein 8

VAMP-8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vamp8 NCBI NCBI:8673