2. Gene
  3. Rbbp8 - retinoblastoma binding protein 8, endonuclease Gene

Rbbp8 - retinoblastoma binding protein 8, endonuclease Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RIM; CtIP; SAE2; RBBP-8; 9930104E21Rik

基因 ID: 225182 | 基因类型: protein coding

关于 Rbbp8

功能概要

Predicted to enable several functions, including DNA binding activity; identical protein binding activity; and single-stranded DNA endodeoxyribonuclease activity. Acts upstream of or within G1/S transition of mitotic cell cycle and blastocyst hatching. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in site of double-strand break. Human ortholog(s) of this gene implicated in Seckel syndrome 2. Orthologous to human RBBP8 (RB binding protein 8, Endonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp8 基因产物(2)

mRNA Protein Name
NM_001081223.2 NP_001074692.1 DNA endonuclease RBBP8
NM_001252495.1 NP_001239424.1 DNA endonuclease RBBP8
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
15831459 MGI
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
15831459 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA endonuclease RBBP8

ctBP-interacting protein

retinoblastoma-binding protein 8

sporulation in the absence of SPO11 protein 2 homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11720 RBBP8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20478 Rbbp8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26986 Rbbp8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rbbp8 NCBI NCBI:5932
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