2. Gene
  3. Ndufs2 - NADH:ubiquinone oxidoreductase core subunit S2 Gene

Ndufs2 - NADH:ubiquinone oxidoreductase core subunit S2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CI-49kD

基因 ID: 226646 | 基因类型: protein coding

关于 Ndufs2

功能概要

Enables NADH dehydrogenase (ubiquinone) activity and oxygen sensor activity. Involved in several processes, including cellular response to oxygen levels; gliogenesis; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; inherited metabolic disorder; multiple sclerosis; and nuclear type mitochondrial complex I deficiency 6. Orthologous to human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2). [provided by Alliance of Genome Resources, Apr 2022]

Ndufs2 基因产物(2)

mRNA Protein Name
NM_153064.5 NP_694704.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial precursor
NM_153064.5 NP_694704.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NADH dehydrogenase (ubiquinone) activity IMP
IMP: 通过突变表型推断
26437605 MGI
enables oxygen sensor activity IMP
IMP: 通过突变表型推断
26437605 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
32279995 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to oxygen levels IMP
IMP: 通过突变表型推断
26437605 MGI
involved in gliogenesis IMP
IMP: 通过突变表型推断
31297047 MGI
involved in mitochondrial respiratory chain complex I assembly IMP
IMP: 通过突变表型推断
26437605 MGI
involved in neural precursor cell proliferation IMP
IMP: 通过突变表型推断
31297047 MGI
involved in neurogenesis IMP
IMP: 通过突变表型推断
31297047 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

NADH dehydrogenase (ubiquinone) Fe-S protein 2

NADH-coenzyme Q reductase

NADH-ubiquinone oxidoreductase 49 kDa subunit

complex I-49kD

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09158 NDUFS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21898 Ndufs2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndufs2 NCBI NCBI:4720
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