ABCF1 - ATP binding cassette subfamily F member 1 Gene

中文名称：ATP 结合盒亚家族 F 成员 1

种属: Homo sapiens

同用名: ABC27; ABC50

关于 ABCF1

功能概要

由该基因编码的蛋白质是 ATP 结合盒 (ABC) 转运蛋白超家族的成员。 ABC 蛋白可跨细胞外膜和细胞内膜转运各种分子。 ABC 基因分为七个不同的亚家族 (ABC1、MDR/TAP、MRP、ALD、OABP、GCN20、White) 。该蛋白是 GCN20 亚家族的成员。与超家族的其他成员不同，这种蛋白质缺乏大多数 ABC 转运蛋白所特有的跨膜结构域。这种蛋白质可能受肿瘤坏死因子-α 的调节，并在增强蛋白质合成和炎症过程中发挥作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike Other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]