1. Gene
  2. Rigi - RNA sensor RIG-I Gene

Rigi - RNA sensor RIG-I Gene

种属: Mus musculus

同用名: Ddx58; RIG-I; RLR-1; C330021E21; 6430573D20Rik

基因 ID: 230073 | 基因类型: protein coding

关于 Rigi

功能概要

Enables double-stranded DNA binding activity; double-stranded RNA binding activity; and single-stranded RNA binding activity. Involved in innate immune response; positive regulation of cytokine production; and response to virus. Acts upstream of or within response to exogenous dsRNA. Predicted to be located in several cellular components, including actin cytoskeleton; bicellular tight junction; and ruffle membrane. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; olfactory epithelium; ovary; and renal calyx. Orthologous to human DDX58 (DExD/H-box helicase 58). [provided by Alliance of Genome Resources, Apr 2022]

Rigi 基因产物(1)

mRNA Protein Name
NM_172689.3 NP_766277.3 antiviral innate immune response receptor RIG-I
蛋白主名 其他名称

antiviral innate immune response receptor RIG-I

ATP-dependent RNA helicase DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

DEAD box protein 58

DEAD/H box helicase 58

DEAD/H box polypeptide RIG-I

RIG-1

RIG-I-like receptor 1

probable ATP-dependent RNA helicase DDX58

retinoic acid-inducible gene 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rigi NCBI NCBI:23586