1. Gene
  2. MON2 - MON2 homolog, regulator of endosome-to-Golgi trafficking Gene

MON2 - MON2 homolog, regulator of endosome-to-Golgi trafficking Gene

中文名称:MON2 同系物,内体到高尔基体运输的调节器

种属: Homo sapiens

基因 ID: 23041 | 基因类型: protein coding

关于 MON2

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:62,466,826-62,600,476 (from NCBI)

This gene has 14 transcripts (splice variants), 209 orthologues and 15 paralogues. Ubiquitous expression in thyroid (RPKM 6.3), ovary (RPKM 5.3) and 25 other tissues.

功能概要

预计参与高尔基体到核内体的运输。位于早期内体膜。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in Golgi to endosome transport. Located in early endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]

MON2 基因产物(5)

mRNA Protein Name
NM_001278469.3 NP_001265398.1 protein MON2 homolog isoform 2
NM_001278470.2 NP_001265399.1 protein MON2 homolog isoform 3
NM_001278471.2 NP_001265400.1 protein MON2 homolog isoform 4
NM_001278472.2 NP_001265401.1 protein MON2 homolog isoform 5
NM_015026.3 NP_055841.2 protein MON2 homolog isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18418388 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in early endosome membrane IDA
IDA: 通过直接分析推断
30213940 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MON2 蛋白结构

Sec7_N

Sec7_N: Guanine nucleotide exchange factor in Golgi transport N-terminal (211 - 286)

Sec7_N

Sec7_N: Guanine nucleotide exchange factor in Golgi transport N-terminal (306 - 386)

DUF1981

DUF1981: Domain of unknown function (DUF1981) (849 - 933)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1718 a.a.
蛋白主名 其他名称

protein MON2 homolog

MON2 regulator of endosome-to-Golgi trafficking

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MON2 VGNC VGNC:43315
Bos taurus MON2 VGNC VGNC:31553
Macaca mulatta MON2 VGNC VGNC:74854
Felis catus MON2 VGNC VGNC:63556
Mus musculus MON2 MGD MGI:1914324
Rattus norvegicus MON2 RGD RGD:1308808