2. Gene
  3. PPRC1 - PPARG related coactivator 1 Gene

PPRC1 - PPARG related coactivator 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：PPARG 相关共激活因子 1

种属: Homo sapiens

同用名: PRC

基因 ID: 23082 | 基因类型: protein coding

关于 PPRC1

Cytogenetic location: 10q24.32 Genomic coordinates (GRCh38): 10:102,119,889-102,150,333 (from NCBI)

This gene has 6 transcripts (splice variants), 257 orthologues and 2 paralogues. Ubiquitous expression in gall bladder (RPKM 7.9), appendix (RPKM 7.5) and 25 other tissues.

功能概要

该基因编码的蛋白质类似于 PPAR-γ 辅激活因子 1 (PPARGC1/PGC-1) ，这种蛋白质可以通过与核呼吸因子 1 (NRF1) 的直接相互作用部分激活线粒体生物发生。这种蛋白质已被证明与 NRF1 相互作用。它被认为是 PPAR-γ 辅激活因子 1 的功能亲属，可通过 NRF1 响应增殖信号激活线粒体生物发生。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 12 月]

The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

PPRC1 基因产物(3)

mRNA Protein Name
NM_001288727.2 NP_001275656.1 peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 2
NM_001288728.2 NP_001275657.1 peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 3
NM_015062.5 NP_055877.3 peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 1

PPRC1 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (1545 - 1604)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1664 a.a.
蛋白主名 其他名称

peroxisome proliferator-activated receptor gamma coactivator-related protein 1

PGC-1-related coactivator

关联疾病

疾病名称 别名
Epithelial Recurrent Erosion Dystrophy

ERED

Corneal Erosions, Recurring Hereditary

Col17a1

Dystrophia Helsinglandica

Dystrophia Smolandiensis

Recurrent Hereditary Corneal Erosions

Rces

Recurrent Corneal Erosion Syndrome

Recurrent Erosion Of Cornea
Oncocytoma

Oxyphilic Adenoma

Follicular Adenoma, Oxyphilic Cell

Adenoma, Oxyphilic

Hurthle Cell Tumor

Oncocytic Neoplasm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11037 PPRC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22740 Pprc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29254 Pprc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PPRC1 VGNC VGNC:33276
Macaca mulatta PPRC1 VGNC VGNC:76343
Felis catus PPRC1 VGNC VGNC:64335
Mus musculus PPRC1 MGD MGI:2385096
Canis familiaris PPRC1 VGNC VGNC:44928
Rattus norvegicus PPRC1 RGD RGD:1309688
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z