2. Gene
  3. Tnip2 - TNFAIP3 interacting protein 2 Gene

Tnip2 - TNFAIP3 interacting protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ABIN-2; 1810020H16Rik

基因 ID: 231130 | 基因类型: protein coding

关于 Tnip2

功能概要

Predicted to enable polyubiquitin modification-dependent protein binding activity and protein kinase binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of leukocyte activation; and Toll-like Receptor signaling pathway. Acts upstream of or within I-kappaB kinase/NF-kappaB signaling. Located in cytoplasm. Orthologous to human TNIP2 (TNFAIP3 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Tnip2 基因产物(1)

mRNA Protein Name
NM_139064.2 NP_620703.1 TNFAIP3-interacting protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IDA
IDA: 通过直接分析推断
11390377 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20060382 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in CD40 signaling pathway IMP
IMP: 通过突变表型推断
16633345 MGI
involved in cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
16633345 MGI
involved in interleukin-1-mediated signaling pathway IMP
IMP: 通过突变表型推断
16633345 MGI
acts upstream of or within negative regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
11390377 MGI
involved in positive regulation of B cell activation IMP
IMP: 通过突变表型推断
16633345 MGI
involved in positive regulation of macrophage activation IMP
IMP: 通过突变表型推断
16633345 MGI
involved in protein stabilization IMP
IMP: 通过突变表型推断
16633345 MGI
involved in toll-like receptor 2 signaling pathway IMP
IMP: 通过突变表型推断
16633345 MGI
involved in toll-like receptor 3 signaling pathway IMP
IMP: 通过突变表型推断
16633345 MGI
involved in toll-like receptor 9 signaling pathway IMP
IMP: 通过突变表型推断
16633345 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
11390377 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TNFAIP3-interacting protein 2

A20 binding inhibitor of NF-kappaB activation-2

A20-binding inhibitor of NF-kappa-B activation 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14835 TNIP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22867 Tnip2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29381 Tnip2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnip2 NCBI NCBI:79155
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