2. Gene
  3. Cnot1 - CCR4-NOT transcription complex, subunit 1 Gene

Cnot1 - CCR4-NOT transcription complex, subunit 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D830048B13; 6030411K04Rik

基因 ID: 234594 | 基因类型: protein coding

关于 Cnot1

功能概要

Predicted to enable armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Involved in regulation of stem cell population maintenance and trophectodermal cell differentiation. Located in P-body. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in holoprosencephaly. Orthologous to human CNOT1 (CCR4-NOT transcription complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Cnot1 基因产物(5)

mRNA Protein Name
NM_001205226.2 NP_001192155.1 CCR4-NOT transcription complex subunit 1 isoform 3
NM_001372351.1 NP_001359280.1 CCR4-NOT transcription complex subunit 1 isoform 4
NM_001372353.1 NP_001359282.1 CCR4-NOT transcription complex subunit 1 isoform 5
NM_153164.4 NP_694804.3 CCR4-NOT transcription complex subunit 1 isoform 1
NM_178078.3 NP_835179.1 CCR4-NOT transcription complex subunit 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17452450 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of stem cell population maintenance IMP
IMP: 通过突变表型推断
22367759 MGI
involved in trophectodermal cell differentiation IMP
IMP: 通过突变表型推断
22367759 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in P-body IDA
IDA: 通过直接分析推断
20133598 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CCR4-NOT transcription complex subunit 1

CCR4-associated factor 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02899 CNOT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22450 Cnot1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28973 Cnot1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnot1 NCBI NCBI:23019
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